purinergic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3280	Clodronate disodium tetrahydrate	clodronic acid disodium tetrahydrate,Disodium clodronate tetrahydrate,Clastoban,Clodronate disodium	IL Receptor , TNF
	Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.		IL Receptor , TNF
T7881	CTP disodium dihydrate		P2X Receptor
	CTP disodium dihydrate is an agonist of P2X4 purinergic receptor		P2X Receptor
T19397	L-Methionine sulfoxide	H-Met(O)-OH	Endogenous Metabolite
	L-Methionine sulfoxide (H-Met(O)-OH) (H-Met(O)-OH) is a metabolite of Methionine. (H-Met(O)-OH) modulates oxidative stress and purinergic signaling parameters, and induces M1/classical macrophage polarization.		Endogenous Metabolite
T4298	JNJ-47965567	JNJ-479655	P2X Receptor
	JNJ-47965567 (JNJ-479655) is a selective antagonist of the purinergic receptor P2X subtype 7 (P2X7), a ligand-gated ion channel(with pKis of 7.9 and 8.7 for human and rat P2X7, respectively).		P2X Receptor
T8946	Indophagolin		P2X Receptor , 5-HT Receptor , Autophagy
	Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.		P2X Receptor , 5-HT Receptor , Autophagy
T23164	PIT	2,2'-Pyridylisatogen tosylate	P2Y Receptor
	PIT (2,2'-Pyridylisatogen tosylate) is a specific and non-competitive antagonist of the Purinergic receptor P2Y1 with an IC50 of 0.14 μM for human P2Y1. PIT does not affect nucleotide binding and can be used in studies a...		P2Y Receptor
T20089	ATP	Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate	Endogenous Metabolite
	ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...		Endogenous Metabolite
T20731	Brilliant blue G-250	BBG,Acid blue 90, Coomassie Brilliant Blue G,Brilliant Blue G	P2X Receptor
	Brilliant blue G-250 (Acid blue 90, Coomassie Brilliant Blue G) is an antagonist of the P2X7 purinergic receptor.		P2X Receptor
T2946	Tanshinone IIA sulfonate sodium	Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium	CaMK , P450 , Calcium Channel
	Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor...		CaMK , P450 , Calcium Channel
T19049	Procion Blue HB	Reactive Blue 2	Others
	Procion Blue HB is an antagonist of purinergic.		Others
T23241	Ro 0437626		Others
	P2X1 purinergic receptor antagonist		Others
T23581	2-Methylthioadenosine diphosphate trisodium	2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP
	2-MeS-ADP is a purinergic agonist that acts by displaying selectivity for P2Y1, P2Y12, and P2Y13 receptors and inhibiting cAMP accumulation.
T70667	KF 20274
	KF 20274 is an adenosine A1 antagonist; purinergic receptor antagonist.
T70450	BMS-870145
	BMS-870145 is a potent and selective P2Y1 purinergic receptor antagonist..
T62488	P2X7 receptor antagonist-1
	P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.
T29730	AGR-540	AGR540
	AGR-540 is a prodrug of AGR-529. AGR-540 has been shown to return plasma triglyceride concentrations to normal levels in mouse models. This effect may be attributed to an interaction of the molecule with A1 purinergic re...
T39891	8-Bromo-ATP	8-Bromoadenosine 5'-triphosphate,8-Bromo-ATP,8-Br-ATP
	8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and an ATP analogue. It exhibits cytotoxicity towards multiple myeloma cells, with an IC50 of 23.1 μM.
T74409	EVT-401
	EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].
T83823	Sp-Uridine-5'-O-(1-thiotriphosphate) sodium	Sp-UTP-α-S
	Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express th...
T83839	Uridine 5'-methylenediphosphate sodium	α,β-methylene UDP,UMP-CP
	Uridine 5’-methylenediphosphate (UMP-CP), a hydrolytically stable derivative of UDP and agonist of the purinergic P2Y14 receptor, exhibits selective inhibition of cAMP production in cells expressing human P2Y14 compared ...