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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T17454 | ATP-polyamine-biotin | Others | |
ATP-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM. ATP-polyamine-biotin i... | |||
T0508 | γ-Aminobutyric acid | Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid | GABA Receptor , Endogenous Metabolite |
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system. | |||
T7508 | N-Acetylputrescine hydrochloride | Endogenous Metabolite | |
N-Acetylputrescine is a polyamine commonly occurring excreted in normal human urine | |||
T19466 | N8-Acetylspermidine dihydrochloride | Endogenous Metabolite | |
N8-Acetylspermidine dihydrochloride is a polyamine. | |||
T19461 | N1,N8-Diacetylspermidine | Endogenous Metabolite | |
N1,N8-Diacetylspermidine is a polyamine found in human urine.N1,N8-Diacetylspermidine can be used as a marker for cancer and malignancy. | |||
T27143 | Delucemine Hydrochloride | NPS 1506,Delucemine,Delucemine HCl,NPS1506,NPS-1506 | NMDAR |
Delucemine Hydrochloride (Delucemine) is a polyamine NMDA receptor antagonist used in the study of neurological disorders such as depression and Alzheimer's disease. | |||
T36416 | N1-Acetylspermine trihydrochloride | N1-Acetylspermine (hydrochloride) | Others |
N1-Acetylspermine trihydrochloride is a monoacetylated derivative of spermine which is an endogenous polyamine. N1-Acetylspermine trihydrochloride can be used in studies about the uptake of the anticancer polyamine anal... | |||
T10313 | AMXT-1501 tetrahydrochloride | Others | |
AMXT-1501 tetrahydrochloride is an inhibitor of polyamine transport. It blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells. | |||
T7849 | Norspermine | Others | |
Norspermine is a polyamine analogue ,used in the treatment of non-small cell lung carcinoma and breast cancer. | |||
T22965 | MDL 72527 | N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride | Others |
MDL 72527 (N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride) is a polyamine oxidase (POA) inhibitor | |||
T3093 | Spermine tetrahydrochloride | Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride | Others , Endogenous Metabolite |
Spermine tetrahydrochloride (Musculamine tetrahydrochloride) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free ... | |||
T3007 | Spermine | Gerontine,Musculamine,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine | Influenza Virus , Endogenous Metabolite |
Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. | |||
T5080 | Spermidine trihydrochloride | Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride | NMDAR , Autophagy |
Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA). | |||
T37170 | N1-Acetylspermidine hydrochloride | N1-Acetylspermidine (hydrochloride) | Endogenous Metabolite |
N1-Acetylspermidine hydrochloride is an acetyl derivative of spermidine. N1-Acetylspermidine hydrochloride is a substrate for the polyamine oxidase and selectively elevates the levels of which in human colorectal adenoca... | |||
T60738 | JNJ-1289 | Smo | |
JNJ-1289 is a selective, potent, and competitive inhibitor of human spermine oxidase (hSMOX) with an IC50 value of 50 nM.JNJ-1289 has potential anticancer and anti-inflammatory activity for the study of polyamine catabol... | |||
T5222 | N-(5-Aminopentyl)acetamide | Monoacetylcadaverine,N-Acetylcadaverine,N-Acetyl-1,5-pentanediamine | Others , Endogenous Metabolite |
N-(5-Aminopentyl)acetamide (N-Acetylcadaverine) is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large doses. N-(5-Am... | |||
T22583 | Arcaine sulfate | NMDAR | |
Arcaine sulfate is a NMDA antagonist. | |||
T1611 | Isotretinoin | 13-cis-Retinoic acid | Retinoid Receptor , Endogenous Metabolite , Autophagy |
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall... | |||
T35617 | Mitoguazone | MGBG,Methyl-GAG | Apoptosis , HIV Protease |
Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with a... | |||
T35449 | α-(difluoromethyl)-DL-Arginine | DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine | Others |
α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been sh... |