Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MDL 72527 (N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride) is a polyamine oxidase (POA) inhibitor
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 428.00 | |
100 mg | In stock | $ 639.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | MDL 72527 (N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride) is a polyamine oxidase (POA) inhibitor |
In vivo | In the absence of CRP, exposure of platelets to MDL-72527 did not significantly modify [Ca2+]i, P-selectin abundance, αIIbβ3 integrin abundance, ROS, annexin-V-binding, and forward scatter. The addition of 2-5 μg/ml CRP was followed by significant increase of [Ca2+]i, P-selectin abundance, αIIbβ3 integrin activation, ROS abundance, annexin-V-binding, and aggregation as well as a significant decrease of forward scatter, all effects significantly blunted or virtually abolished in the presence of MDL-72527. MDL-72527 is a powerful inhibitor of platelet activation, apoptosis and aggregation[1]. |
Synonyms | N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride |
Molecular Weight | 265.22 |
Formula | C12H22Cl2N2 |
CAS No. | 93565-01-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/ml (75.41 mM)
You can also refer to dose conversion for different animals. More
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MDL 72527 93565-01-6 Others N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine MDL72527 MDL-72527 N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride inhibitor inhibit