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Search Results for " pa2 "

20

Compounds

Cat No. Product Name Synonyms Targets
T81576 PA22-2 IKVAV sequence,Laminin A-chain fragment
PA22-2, an active biological peptide featuring the IKVAV sequence from the laminin A-chain fragment, is derived from mouse laminin alpha1 amino acid residues 2110-2127. Substrates composed of PA22-2 have been shown to fa...
T15786 LPA2 antagonist 1 Hydroxylase
LPA2 antagonist 1 is an LPA2 antagonist (IC50: 17 nM).
T81575 PA22-2 free acid Cys-Laminin A chain 2091-2108
PA22-2 (free acid) (Cys-Laminin A chain 2091-2108), a peptide, promotes neurite outgrowth and facilitates the formation of neuron-like processes. It is utilized in the culturing of human adenoid cystic carcinoma cells an...
T73237 GTPA2-OMe
gTPA2-OMe is a potential hole transport layer candidate for perovskite solar cells (PSCs).
T11875 LPA2 antagonist 2 LPA Receptor
LPA2 antagonist 2 is >480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM.
T16798 RS 17053 hydrochloride RS-17053 Others , Adrenergic Receptor
RS 17053 hydrochloride is a potent and selective antagonist of α1A adrenoceptor. RS 17053 hydrochloride exhibits a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays.
TP1933 R715 TFA(185052-09-9 free base) R 715 Bradykinin Receptor
R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Me...
T7817 Aprocitentan ACT-132577 Endothelin Receptor
Aprocitentan (ACT-132577) is ETA and ETB antagonist .
T15682 L-371,257 Oxytocin Receptor , Vasopressin Receptor
L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.
T11723L JNJ-39758979 Histamine Receptor
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine...
T10249 Adoprazine SLV313 Others
Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
T8899 Metipranolol Adrenergic Receptor
Metipranolol (Betamann) is a type of β- Adrenergic receptors( β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta bloc...
T22921 LE 300 Dopamine Receptor , 5-HT Receptor
dopamine D1 receptor antagonist
T8004 SNAP 94847 hydrochloride GPR , Melanin-concentrating Hormone Receptor (MCHR)
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
T6364 Desfesoterodine 5-HMT,(R)-5-Hydroxymethyl Tolterodine,PNU-200577,5-HM,5-hydroxymethyl Tolterodine AChR
Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
T10516 Beperidium iodide SX 810 Others
Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).
T15647 Tipelukast MN 001,KCA 757 Leukotriene Receptor
Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1, type 1 collagen.Tipelukast is used in the study of asthma.
T13163 Tiotidine ICI 125211 Others
Tiotidine is a selective histamine H2-receptor antagonist (pA2=7.3-7.8 for guinea-pig right atrium).
T76427 (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B functions as a competitive antagonist to the Neurokinin B receptor, exhibiting a pA2 value of 5.5. Notably, it does not affect Substance P or Neurokinin A [1].
T30880 Chir 2279 Chir2279
Chir 2279 is a N-(substituted)glycine peptoid trimer with high-affinity binding for alpha 1-adrenoceptors. CHIR 2279 antagonized the epinephrine-induced increase in intraurethal pressure (pseudo pA2, 6.86) in dogs.
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