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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81576 | PA22-2 | IKVAV sequence,Laminin A-chain fragment | |
PA22-2, an active biological peptide featuring the IKVAV sequence from the laminin A-chain fragment, is derived from mouse laminin alpha1 amino acid residues 2110-2127. Substrates composed of PA22-2 have been shown to fa... | |||
T15786 | LPA2 antagonist 1 | Hydroxylase | |
LPA2 antagonist 1 is an LPA2 antagonist (IC50: 17 nM). | |||
T81575 | PA22-2 free acid | Cys-Laminin A chain 2091-2108 | |
PA22-2 (free acid) (Cys-Laminin A chain 2091-2108), a peptide, promotes neurite outgrowth and facilitates the formation of neuron-like processes. It is utilized in the culturing of human adenoid cystic carcinoma cells an... | |||
T73237 | GTPA2-OMe | ||
gTPA2-OMe is a potential hole transport layer candidate for perovskite solar cells (PSCs). | |||
T11875 | LPA2 antagonist 2 | LPA Receptor | |
LPA2 antagonist 2 is >480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. | |||
T16798 | RS 17053 hydrochloride | RS-17053 | Others , Adrenergic Receptor |
RS 17053 hydrochloride is a potent and selective antagonist of α1A adrenoceptor. RS 17053 hydrochloride exhibits a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. | |||
TP1933 | R715 TFA(185052-09-9 free base) | R 715 | Bradykinin Receptor |
R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Me... | |||
T7817 | Aprocitentan | ACT-132577 | Endothelin Receptor |
Aprocitentan (ACT-132577) is ETA and ETB antagonist . | |||
T15682 | L-371,257 | Oxytocin Receptor , Vasopressin Receptor | |
L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a. | |||
T11723L | JNJ-39758979 | Histamine Receptor | |
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine... | |||
T10249 | Adoprazine | SLV313 | Others |
Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties. | |||
T8899 | Metipranolol | Adrenergic Receptor | |
Metipranolol (Betamann) is a type of β- Adrenergic receptors( β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta bloc... | |||
T22921 | LE 300 | Dopamine Receptor , 5-HT Receptor | |
dopamine D1 receptor antagonist | |||
T8004 | SNAP 94847 hydrochloride | GPR , Melanin-concentrating Hormone Receptor (MCHR) | |
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM) | |||
T6364 | Desfesoterodine | 5-HMT,(R)-5-Hydroxymethyl Tolterodine,PNU-200577,5-HM,5-hydroxymethyl Tolterodine | AChR |
Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM. | |||
T10516 | Beperidium iodide | SX 810 | Others |
Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93). | |||
T15647 | Tipelukast | MN 001,KCA 757 | Leukotriene Receptor |
Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1, type 1 collagen.Tipelukast is used in the study of asthma. | |||
T13163 | Tiotidine | ICI 125211 | Others |
Tiotidine is a selective histamine H2-receptor antagonist (pA2=7.3-7.8 for guinea-pig right atrium). | |||
T76427 | (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B | ||
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B functions as a competitive antagonist to the Neurokinin B receptor, exhibiting a pA2 value of 5.5. Notably, it does not affect Substance P or Neurokinin A [1]. | |||
T30880 | Chir 2279 | Chir2279 | |
Chir 2279 is a N-(substituted)glycine peptoid trimer with high-affinity binding for alpha 1-adrenoceptors. CHIR 2279 antagonized the epinephrine-induced increase in intraurethal pressure (pseudo pA2, 6.86) in dogs. |