Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Metipranolol (Betamann) is a type of β- Adrenergic receptors( β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta blocking potentials (pA2) of 8.3 and 8.4, respectively. It is also a potent substituent in the 3H DHA binding assay, with a ligand concentration of 0.7 nM and a Ki of 39 ± 24 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 80.00 | |
25 mg | In stock | $ 178.00 | |
50 mg | In stock | $ 312.00 | |
100 mg | In stock | $ 506.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | Metipranolol (Betamann) is a type of β- Adrenergic receptors( β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta blocking potentials (pA2) of 8.3 and 8.4, respectively. It is also a potent substituent in the 3H DHA binding assay, with a ligand concentration of 0.7 nM and a Ki of 39 ± 24 nM. |
In vivo | Metipranolol applied as eye drops promoted cone photoreceptor function in retinas of rd10 mice greater than subcutaneously injected metipranolol.?The reduced nitrosative damage and rescue of functional loss of photoreceptors in rd10 mice suggests that metipranolol, a drug with established ocular safety and tolerability, may have potential for treating patients with retinitis pigmentosa[1]. |
Molecular Weight | 309.4 |
Formula | C17H27NO4 |
CAS No. | 22664-55-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (80.8 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Metipranolol 22664-55-7 GPCR/G Protein Neuroscience Adrenergic Receptor stress Beta Receptor glaucoma lipid antioxidant peroxidation inhibit Nitrosative Inhibitor hypertension inhibitor