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Search Results for " multidrug-resistant "

20

Compounds

Cat No. Product Name Synonyms Targets
T11888 LtaS-IN-1 Others , Antibacterial
LtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 is against Enterococcus spp 28 strains with varying MIC value...
T4989 Fosfomycin Tromethamine Antibacterial , Antibiotic
An antibiotic produced by Streptomyces fradiae.
T8262 Fosfomycin sodium Fosfomycin Disodium Antibacterial , Antibiotic
Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an e...
T3131 Fosfomycin calcium Phosphomycin calcium salt,Fosmicin Antibacterial , Antibiotic
Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.
T1631 Sulbactam CP45899 Antibacterial , Antibiotic
Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabol...
T6685 Sulbactam sodium CP-45899-2 Antibacterial , Antibiotic
Sulbactam sodium (CP-45899-2) (Unasyn) is an irreversible β-lactamase inhibitor.
T10460 Batabulin T138067 Apoptosis , Microtubule Associated
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to ce...
T1589 D-Cycloserine RO-1-9213 Others , Antibacterial , Antibiotic , iGluR
D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.
T22330 Fenamic acid 2-Anilinobenzoic acid,Diphenylamine-2-carboxylic acid,2-(Phenylamino)benzoic acid,N-Phenylanthranilic acid Chloride channel
Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), inc...
T10378 Artelinic acid Others
Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug-resistant strains of Plasmodium falciparum.
T5757 Loganetin Antibacterial
Loganetin, a non-toxic natural product, shows antibacterial activity against multidrug-resistant Gram-negative infections.
T9982 PU23 MRP
PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
TN1342 8-Epidiosbulbin E acetate Anti-infection , Antibacterial
8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.
T22269 Benzyldodecyldimethylammonium Chloride Dihydrate Antibacterial
Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino...
T5A2455 Arenobufagin Others
Arenobufagin is a natural bufadienolide from toad venom with potent antineoplastic activity against HCC HepG2 cells and corresponding multidrug-resistant HepG2/ADM cells.
T22382 NSC 31150 Others
NSC 31150 is a bioactive chemical.
T15409 GNF179 Parasite
GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
TN4221 Homoembelin 2,5-dihydroxy-3-nonyl-1,4-benzoquinone Antibacterial
Homoembelin (2,5-dihydroxy-3-nonyl-1,4-benzoquinone) is a pigment from E. ribes and C. monocarpus that has antibacterial effects and can be used to study multidrug-resistant bacterial infections.
T9830 GSK2556286 GSK286 Antibacterial
GSK2556286 (GSK286) is an orally active inhibitor of Mycobacterium tuberculosis (M. tuberculosis).GSK2556286 inhibits the growth of human macrophages with an IC50 value of 0.07 μM.GSK2556286 is effective against both mul...
T2S0271 Voacamine Voacanginine Cannabinoid Receptor , P-gp
Voacamine (Voacanginine) is an indole alkaloid. Voacamine exhibits potent cannabinoid CB1 receptor antagonistic activity. Voacamine also inhibits P-glycoprotein (P-gp) action in multidrug-resistant tumor cells.Voacangini...
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