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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1104L | Melanin Concentrating Hormone, salmon acetate | MCH (salmon),Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base) | Others , Melanin-concentrating Hormone Receptor (MCHR) |
Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. | |||
T38855 | Melanin probe-1 | ||
Melanin probe-1, an 18F-picolinamide-based PET probe, is utilized for PET imaging of malignant melanoma. It demonstrates remarkable tumor targeting efficacy, superior tumor imaging contrasts, favorable biodistribution pr... | |||
TP1104 | Melanin Concentrating Hormone, salmon | MCH (salmon) | |
Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. | |||
T64640 | Melanin probe-2 | ||
Melanoma is a lethal skin cancer. The early detection of melanoma using positron emission tomography (PET) probes is critical for improving the survival of melanoma patients. Melanin probe-2 is a non-radioactive bromo-pi... | |||
T75970 | Melanin Concentrating Hormone, salmon TFA | ||
Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a 19-amino-acid neuropeptide discovered in teleost fish's pituitary gland, involved in controlling food intake, energy balance, sleep states, and cardiovasc... | |||
T3816 | Velutin | NF-κB , HIF/HIF Prolyl-Hydroxylase | |
Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ... | |||
T11966 | MCHR1 antagonist 2 | HER , Melanin-concentrating Hormone Receptor (MCHR) | |
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG. | |||
TN1545 | D-Tyrosine | Tyrosinase | |
D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits biofilm formation and induces the self-dispersal of biofilm... | |||
TP1102 | MCH (salmon) TFA (87218-84-6 free base) | Melanin Concentrating Hormone, salmon TFA,MCH (salmon) TFA | |
Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. Melanin Concentrating Hormone is implicated in the control of general arousal and goal-orientated behaviours ... | |||
T9135 | Epirosmanol | Others | |
Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa). | |||
T5826 | Eupalinolide A | HSP | |
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines. | |||
T7052 | Gnetol | Tyrosinase , COX , HDAC , AChR | |
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ... | |||
TN6901 | Methyl myristate | methyl tetradecanoate | Others |
Methyl myristate (methyl tetradecanoate) is a natural product. | |||
TP1996 | MCH(human, mouse, rat) | MCH (human, mouse, rat) | GPR , Melanin-concentrating Hormone Receptor (MCHR) |
MCH(human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively). Increase... | |||
T8244 | Raspberry ketone glucoside | Others | |
Raspberry ketone glucoside is a natural product in raspberry fruit, has lasting effects for the inhibition of melanogenesis and various melanogenic factors after the degradation in the skin. | |||
T8004 | SNAP 94847 hydrochloride | GPR , Melanin-concentrating Hormone Receptor (MCHR) | |
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM) | |||
T1310 | 2-Thiouracil | Thiouracil,Deracil | Thyroid hormone receptor(THR) , NO Synthase |
2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent. | |||
T2P2810 | Methyl Linoleate | Linoleic acid methyl ester,Telfairic Acid methyl ester | Antioxidant |
Methyl Linoleate (Telfairic Acid methyl ester) linoleate has antioxidant activity. | |||
T2819 | Methyl p-coumarate | Methyl 4-hydroxycinnamate | Others , Antifungal |
"Methyl 4-hydroxycinnamate is an esterified derivative of p-coumaric acid isolated from the flowers of Trixis michuacana var. longifolia, exhibiting antibacterial and anti-melanogenesis properties." | |||
T7769 | Nonapeptide-1 | Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,Melanostatine™ 5 | Others |
Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions. |