lanosterol — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4970	LANOSTEROL	3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol	Endogenous Metabolite
	Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.		Endogenous Metabolite
T32558	Lanosteryl acetate	Lanosterol acetate
	Lanosteryl acetate is a bioactive chemical.
T8490	Butoconazole	1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole	Antifungal
	Butoconazole (1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole) is an imidazole antifungal agent		Antifungal
T1011	Itraconazole	R51211	P450 , Hedgehog/Smoothened , Antibiotic , Autophagy , Antifungal
	Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
TN6736	Dihydrolanosterol	24,25-Dihydrolanosterol,Lanostenol	Others
	Dihydrolanosterol (24,25-Dihydrolanosterol) is a sterol and the C24-25 hydrogenated products of lanosterol, dihydrolanosterol can be demethylated by mammal or yeast cytochrome P450 sterol 14alpha-demethylase		Others
T41052	24,25-Dihydrolanosterol	Lanostenol
	24,25-Dihydrolanosterol (Lanostenol) is a chemical compound found in the seeds of the red pepper (Capsicum annuum).
T3934	Isavuconazonium sulfate		Antifungal
	Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), wh...		Antifungal
T7866	Difenoconazole		Others , Antifungal
	Difenoconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell ...		Others , Antifungal
T5966	Hexaconazole	(-)-Hexaconazol	Reactive Oxygen Species , Antifungal
	Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of ...		Reactive Oxygen Species , Antifungal
T1438	Butoconazole nitrate	RS 35887	Estrogen/progestogen Receptor , Antifungal
	Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversi...		Estrogen/progestogen Receptor , Antifungal
T1187	Bifonazole	Bay H-4502	P450 , Antibiotic , Antifungal
	Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essent...		P450 , Antibiotic , Antifungal
T1290	Oxiconazole nitrate	Ro 13-8996	Others , Antibiotic , Antifection , Antifungal
	Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole...		Others , Antibiotic , Antifection , Antifungal
T4039	BIBB 515		Others
	BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...		Others
T25625	Lanomycin
	Lanomycin, isolated from Pycnidiophora dispersa, inhibits lanosterol 14alpha-demethylase.
T25127	Azalanstat	RS-21607,RS 21607,RS21607
	Azalanstat is a lanosterol 14 alpha-demethylase inhibitor. The enzyme catalyzes the first step in the conversion of lanosterol to cholesterol in mammals.
T71536	Mdl 28815
	Mdl 28815 is a potent inhibitor of 2,3-oxidosqualene cycloartenol & lanosterol cyclases.
T26191	SK&F 104976	SK&F104976,Skf104976,Skf 104976,SK&F-104976,Skf-104976
	SK&F 104976 is a 32-carboxylic acid derivative of lanosterol. It was found to be a potent lanosterol 14 alpha-demethylase (14 alpha DM) inhibitor.
T32095	Holothurinogenin	Nobilisidenol A
	Holothurinogenin, as a lanosterol derivative, has toxic to nerve tissue.
T69167	Buthiobate
	Buthiobate is a fungicide which inhibits lanosterol 14 alpha-demethylation catalyzed by a cytochrome P-450.
T26424	A 60586	A60586,A-60586
	A 60586, a non-azole inhibitor of ergosterol biosynthesis, inhibits lanosterol 14alpha-demethylase and displays in-vitro antifungal activity.