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Hexaconazole

Catalog No. T5966 CAS 79983-71-4

Synonyms: 己唑醇, (-)-Hexaconazol

Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death.

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Hexaconazole, CAS 79983-71-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death.
In vitro	Hexaconazole is fungicidal against the powdery mildews B. graminis and S. cucurbitae on cucumber plants in a concentration-dependent manner and is curative against powdery mildew on barley plants when used at a concentration of 6.7 mg/L[1].It also inhibits growth of R. bataticola and S. rolfsii (ED50s = 6.35 and 1.27 mg/L, respectively)[2].
Cell Research	The medium was poured into a set of two petriplates under aseptic conditions in a laminar flow hood.?When the medium in the plates was solidified, a mycelial disc of 0.5 cm diameter of freshly grown test fungi taken from periphery was inoculated upside down at the center of the plates.?These treated petri dishes were incubated at 28℃ until fungal growth in the control plates was almost complete.?Hexaconazole used as commercial fungicide and acetone served as control.?All the compounds were tested in triplicates.?The mycelia growth of fungi (mm) in both treated (T) and control (C) petri plates was measured diametrically in three different directions and growth inhibition (I) and corrected inhibition (IC) were calculated by using Abbott s formula[2]

Synonyms	己唑醇, (-)-Hexaconazol
Molecular Weight	314.21
Formula	C14H17Cl2N3O
CAS No.	79983-71-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 100 mg/mL (318.26 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Tsuda M , Itoh H , Kato S . Evaluation of the systemic activity of simeconazole in comparison with that of other DMI fungicides[J]. Pest Management Science, 2004, 60(9):875-880. 2. Shakil N A , Kumar J , Pankaj, , et al. Synthesis and pesticidal activity of new N-alkyl-N-[1-(2-hydroxyphenyl) ethyl]amines[J]. Journal of Environmental Science and Health, Part B, 2009, 44(4):344-349.

Related compound libraries

This product is contained In the following compound libraries：

Antibiotics Library Immunology/Inflammation Compound Library Anti-Fungal Compound Library Anti-Aging Compound Library Bioactive Compound Library

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Keywords

Hexaconazole 79983-71-4 NF-Kb信号通路代谢免疫与炎症微生物学 Antifungal Reactive Oxygen Species inhibit Inhibitor (-)-Hexaconazol Fungal inhibitor

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