joints — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12564	Prudomestin	3,5,7-Trihydroxy-4',8-dimethoxyflavone	Xanthine Oxidase
	Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) is a natural product isolated from the heartwood of Prunus domestica, with xanthine oxidase (XO) inhibitory activity with IC50 of 6 µM.		Xanthine Oxidase
T2O2683	L-Proline	L-(-)-Proline,proline	Endogenous Metabolite
	L-Proline (proline) is a nonessential amino acid in humans. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles.		Endogenous Metabolite
T1303	Auranofin	SKF-39162	Others , SARS-CoV , Antibacterial
	Auranofin (SKF-39162) is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness.		Others , SARS-CoV , Antibacterial
T4S1050	Pristimerin	Celastrol methyl ester	NF-κB , Antibacterial
	1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...		NF-κB , Antibacterial
T4746	Purine	7H-Imidazo(4,5-d)pyrimidine	Others , Endogenous Metabolite
	Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f...		Others , Endogenous Metabolite
T64264	ISIS 104838
	ISIS 104838 is an antisense oligonucleotide that inhibits the production of tumour necrosis factor (TNF-alpha), which causes pain and swelling in rheumatoid arthritis joints.
T80592	Ledelabricin alfa		Endogenous Metabolite
	Ledelabricin alfa, an isoform A variant of human proteoglycan 4 (PRG4), functions as a lubricant for joints and boundaries. It is utilized in the study of arthropathy [1].		Endogenous Metabolite
T1120L2	Dacarbazine citrate	DTIC citrate
	Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Sof...
T71288	Phenylbutazone-d9
	Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity...
TN5153	Torilin		MMP , ERK , IκB/IKK , p38 MAPK , NF-κB , Tyrosinase , Reductase , DNA/RNA Synthesis , JNK
	Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than fi...