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Purine

Catalog No. T4746   CAS 120-73-0
Synonyms: 7H-Imidazo(4,5-d)pyrimidine

Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines from food (or from tissue turnover) are metabolised by several enzymes, including xanthine oxidase, into uric acid. High levels of uric acid can predispose to gout when the acid crystalises in joints; this phenomenon only happens in humans and some animal species (e.g. dogs) that lack an intrinsic uricase enzyme that can further degrade uric acid.

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Purine Chemical Structure
Purine, CAS 120-73-0
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100 mg In stock $ 42.00
1 mL * 10 mM (in DMSO) In stock $ 46.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines from food (or from tissue turnover) are metabolised by several enzymes, including xanthine oxidase, into uric acid. High levels of uric acid can predispose to gout when the acid crystalises in joints; this phenomenon only happens in humans and some animal species (e.g. dogs) that lack an intrinsic uricase enzyme that can further degrade uric acid.
Synonyms 7H-Imidazo(4,5-d)pyrimidine
Molecular Weight 120.11
Formula C5H4N4
CAS No. 120-73-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 22.5 mg/mL (187.32 mM)

TargetMolReferences and Literature

1. Gudbjornsson B, et al. Hypoxanthine, xanthine, and urate in synovial fluid from patients with inflammatory arthritides. Ann Rheum Dis. 1991 Oct;50(10):669-72.

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library Tobacco Monomer Library Traditional Chinese Medicine Monomer Library Human Endogenous Metabolite Library DNA Damage & Repair Compound Library FDA-Approved & Pharmacopeia Drug Library Natural Product Library Clinical Compound Library Bioactive Compounds Library Max Human Endogenous Metabolite Compound Library Plus

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Keywords

Purine 120-73-0 Metabolism Others Endogenous Metabolite 7H-Imidazo(4,5-d)pyrimidine NSC-753 7H-Purine Inhibitor inhibit Isopurine β-Purine NSC753 3,5,7-Triazaindole Purine (6CI,8CI) NSC 753 inhibitor

 

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