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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11580 | Heme Oxygenase-1-IN-1 | HO-1-IN-1 | Reactive Oxygen Species |
Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM). | |||
T32054 | Heme arginate | Hemearginat,Heme arginate complex,Normosang | |
Heme arginine (or heme arginine) is a compound of heme and arginine used to treat acute porphyria by reducing the excessive production of δ-aminolevulinic acid, which causes acute symptoms during the onset of acute porph... | |||
T8948 | Ferroheme | protoheme,Hematin,heme | Others |
Ferroheme (protoheme) is the color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. A Ferroheme or haem is a prosthetic group that consists of an iron atom c... | |||
T11580L | Heme Oxygenase-1-IN-1 hydrochloride | HO-1-IN-1 hydrochloride | Others |
HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM). | |||
T60847 | Heme Oxygenase-2-IN-1 | ||
Heme Oxygenase-2-IN-1 (Compound 9) is a potent, selective inhibitor of heme oxygenase-2 (HO-2). The IC 50 values of Heme Oxygenase-2-IN-1 for HO-1 and HO-2 are 14.9 μM and 0.9 μM, respectively [1]. | |||
T61078 | Heme Oxygenase-1-IN-2 | ||
Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM. | |||
T83193 | Acetyl-Heme-Binding Protein 1 (1-21) (human) | ||
Acetyl-Heme-Binding Protein 1 (1-21) (human) is a short peptide comprising the initial 21 amino acids of the hemopexin Acetyl-Heme-Binding Protein 1, which is involved in heme binding, heme metabolism, and the release of... | |||
T2934 | Bilirubin | Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin | Endogenous Metabolite |
Bilirubin (Principal bile pigment) is a principal pigment of bile and one of the major end products of hemoglobin decomposition. | |||
T13396 | Zinc Protoporphyrin | Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX | Apoptosis , Reactive Oxygen Species , Endogenous Metabolite |
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-can... | |||
TP1617L | Chemerin-9 (149-157) acetate | Chemerin-9 (149-157) acetate (676367-27-4 free base) | Others |
Chemerin-9 (149-157) acetate, The nonapeptide 149,YFPGQFAFS157 (chemerin-9), corresponding to the C terminus of processed chemerin, retained most of the activity of the full-size protein, with regard to agonism toward th... | |||
TP1617 | Chemerin-9 (149-157) | Chemerin-9 149-157 | |
The nonapeptide 149,YFPGQFAFS157 (chemerin-9), corresponding to the C terminus of processed chemerin, retained most of the activity of the full-size protein, with regard to agonism toward the chemerinR.the natural ligand... | |||
T76022 | Chemerin-9 (149-157) (TFA) | ||
Chemerin-9 (149-157) TFA is a potent CMKLR1 (chemokine-like receptor 1) agonist with anti-inflammatory properties. It activates phosphorylation of Akt and ERK and induces ROS production, beneficially modulating immune re... | |||
T74017 | N-Methylhemeanthidine chloride | ||
N-Methylhemeanthidine chloride, an alkaloid derived from Zephyranthes candida of the Amaryllidaceae family, exhibits antitumor properties. It hinders cancer cell proliferation by down-regulating AKT activation, enforcing... | |||
TP1435 | Chemerin-9 (149-157) TFA(676367-27-4 free base) | Chemerin-9 (149-157) (TFA) | |
Chemerin-9 (149-157) TFA, the nonapeptide (149)YFPGQFAFS(157) (chemerin-9), corresponding to the C terminus of processed chemerin, retains most of the activity of the full-size protein, with regard to agonism toward the ... | |||
T37128 | Chemerin-9, Mouse | ||
Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156. | |||
T11901 | IDO1-IN-5 | IDO , Indoleamine 2,3-Dioxygenase (IDO) | |
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. | |||
T40732 | TMPD dihydrochloride | ||
TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases. | |||
T4977 | Sofalcone | SU-88 | Antibacterial , Autophagy |
Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium. | |||
T8273 | 4,6-Dioxoheptanoic acid | Succinylacetone | Others , Endogenous Metabolite |
4,6-Dioxoheptanoic acid (Succinylacetone) acts as a potent inhibitor of heme biosynthesis. | |||
T5515 | Hemin | Hemin chloride | Mitophagy , Ferroptosis , Autophagy |
Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme deficiency in patients, thereby inhibiting δ-aminolevulini... |