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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8680 | FIBROBLAST GROWTH FACTOR, BASIC, HUMAN | ||
FIBROBLAST GROWTH FACTOR, BASIC, HUMAN is a useful organic compound for research related to life sciences. The catalog number is T8680 and the CAS number is 62031-54-3. | |||
T37819 | Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt) | ||
Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that... | |||
T37595 | Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt) | ||
Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that h... | |||
T37820 | Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt) | ||
Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retin... | |||
T76321 | Brain Derived Basic Fibroblast Growth Factor (1-24) | ||
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24), a synthetic peptide, exhibits anti-bacterial and anti-HBV properties, finding application in infectious and immune disease research [1]. | |||
T9030 | SU4984 | FGFR , IGF-1R , PDGFR | |
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1). | |||
T6082 | SSR128129E | SSR | FGFR |
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs. | |||
T6836 | FIIN-2 | FGFR | |
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively. | |||
T9008 | NPD8733 | Others | |
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. It specifically binds to valosin-containing protein (VCP)/p97. | |||
T2347 | BLU9931 | FGFR | |
BLU9931 is the first selective small molecule inhibitor of FGFR4. | |||
T1948 | AZD4547 | VEGFR , FGFR | |
AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays). | |||
TQ0256 | FGFR4-IN-1 | FGFR | |
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM). | |||
T38155 | N-Acetyl-D-cysteine | Reactive Oxygen Species | |
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group. | |||
T3492 | PD-166866 | PD166866 | FGFR , Autophagy |
PD-166866 is a selective FGFR tyrosine kinase inhibitor. | |||
T3714 | SUN11602 | SUN 11602 | ERK , FGFR |
SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. It mimics the neuroprotective effects of bFGF and prevents glutamate-induced neuronal death. It also increases level... | |||
T37512 | Cis-4-Hydroxy-L-proline | Endogenous Metabolite | |
cis-L-Hydroxyproline inhibits the synthesis and extracellular deposition of collagen. The growth inhibition of pancreatic cancer cells induced by the Hyp isomer could be due to endoplasmatic reticulum stress. | |||
T2361 | LY2874455 | LY 2874455,LY-2874455 | VEGFR , FGFR |
LY2874455 has been used in trials studying the treatment of Advanced Cancer. | |||
T5473 | ASP5878 | ASP-5878 | FGFR |
ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L. | |||
T16781 | Rogaratinib | BAY1163877 | FGFR |
Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity. | |||
T3274 | S49076 | FGFR , c-Met/HGFR , TAM Receptor | |
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs. |