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Search Results for " fibroblast "

20

Compounds

Cat No. Product Name Synonyms Targets
T8680 FIBROBLAST GROWTH FACTOR, BASIC, HUMAN
FIBROBLAST GROWTH FACTOR, BASIC, HUMAN is a useful organic compound for research related to life sciences. The catalog number is T8680 and the CAS number is 62031-54-3.
T37819 Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)
Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that...
T37595 Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)
Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that h...
T37820 Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)
Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retin...
T76321 Brain Derived Basic Fibroblast Growth Factor (1-24)
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24), a synthetic peptide, exhibits anti-bacterial and anti-HBV properties, finding application in infectious and immune disease research [1].
T9030 SU4984 FGFR , IGF-1R , PDGFR
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
T6082 SSR128129E SSR FGFR
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.
T6836 FIIN-2 FGFR
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.
T9008 NPD8733 Others
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. It specifically binds to valosin-containing protein (VCP)/p97.
T2347 BLU9931 FGFR
BLU9931 is the first selective small molecule inhibitor of FGFR4.
T1948 AZD4547 VEGFR , FGFR
AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).
TQ0256 FGFR4-IN-1 FGFR
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
T38155 N-Acetyl-D-cysteine Reactive Oxygen Species
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.
T3492 PD-166866 PD166866 FGFR , Autophagy
PD-166866 is a selective FGFR tyrosine kinase inhibitor.
T3714 SUN11602 SUN 11602 ERK , FGFR
SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. It mimics the neuroprotective effects of bFGF and prevents glutamate-induced neuronal death. It also increases level...
T37512 Cis-4-Hydroxy-L-proline Endogenous Metabolite
cis-L-Hydroxyproline inhibits the synthesis and extracellular deposition of collagen. The growth inhibition of pancreatic cancer cells induced by the Hyp isomer could be due to endoplasmatic reticulum stress.
T2361 LY2874455 LY 2874455,LY-2874455 VEGFR , FGFR
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
T5473 ASP5878 ASP-5878 FGFR
ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.
T16781 Rogaratinib BAY1163877 FGFR
Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity.
T3274 S49076 FGFR , c-Met/HGFR , TAM Receptor
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.
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