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Catalog No. T38155   CAS 26117-28-2

N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.

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N-Acetyl-D-cysteine Chemical Structure
N-Acetyl-D-cysteine, CAS 26117-28-2
Pack Size Availability Price/USD Quantity
10 mg In stock $ 37.00
25 mg In stock $ 59.00
50 mg In stock $ 72.00
100 mg In stock $ 122.00
200 mg In stock $ 178.00
500 mg In stock $ 297.00
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Purity: 99.63%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.
In vitro Consistent with the known stereoselectivity of many biological processes, the unnatural D isomer of N-acetylcysteine failed to increase hepatic glutathione. Liver concentrations remained similar to control suggesting that the D isomer was unable to increase the rate of glutathione synthesis. The D isomer further differed from its L enantiomer in failing to increase the plasma concentration and the urinary excretion of inorganic sulfate. Congruent with these observations, much more N-acetyl-D-cysteine (47% of dose) was recovered unchanged in 24 hr urine than N-acetyl-L-cysteine (6.1% of dose)[2].
Molecular Weight 163.19
Formula C5H9NO3S
CAS No. 26117-28-2


Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 250 mg/mL (1531.96 mM)

TargetMolReferences and Literature

1. Suparna Qanungo, et al. N-Acetyl-L-cysteine Enhances Apoptosis Through Inhibition of Nuclear factor-kappaB in Hypoxic Murine Embryonic Fibroblasts. J Biol Chem 2. Maika Deffieu, et al. Glutathione Participates in the Regulation of Mitophagy in Yeast.J Biol Chem. 2009 May 29;284(22):14828-37. 3. B K Wong,et al. Selective Effects of N-acetylcysteine Stereoisomers on Hepatic Glutathione and Plasma Sulfate in Mice. Toxicol Appl Pharmacol


1. Liu Y, Wang Z, Jin H, et al.Squalene-epoxidase-catalyzed 24 (S), 25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity.Cell Reports.2024, 43(4).

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compounds Library Max Anti-Prostate Cancer Compound Library Human Metabolite Library NF-κB Signaling Compound Library Cuproptosis Compound Library Bioactive Compound Library Pyroptosis Compound Library Anti-Breast Cancer Compound Library Antioxidant Compound Library Covalent Inhibitor Library

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N-Acetyl-D-cysteine 26117-28-2 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species murine embryonic NAcetylDcysteine GSH glutathione fibroblast Inhibitor N Acetyl D cysteine inhibit MEF inhibitor