endotoxin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2325L	Endotoxin Inhibitor acetate(147396-10-9 free base)		Others
	Endotoxin Inhibitor acetate has a strong blocking effect on bacterial physiological activity, thus producing antibacterial toxin Inhibitor sequences with disulfide bonds and a large amount of lysine. Endotoxin Inhibitor ...		Others
T78032	Endotoxin inhibitor TFA
	Endotoxin Inhibitor TFA is a synthetic peptide that exhibits high-affinity binding to lipid A, effectively detoxifying LPS and impeding LPS-induced cytokine release in vivo. It also suppresses the febrile response to LPS...
T82468	Endotoxin Substrate
	Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate utilized for the quantitative assays of endotoxin [1].
T27695	JTE-607	JTE-607 dihydrochloride,JTE-607 HCl	Cysteine Protease
	JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.		Cysteine Protease
TP2266L	LF 11 acetate	LF 11 acetate(832729-13-2 Free base)	Antibacterial
	LF 11 acetate exhibits antibacterial activities and can be used for the development of endotoxin-neutralizing and antibacterial agents.		Antibacterial
T2S0765	Epibetulinic acid		NO Synthase , Prostaglandin Receptor
	Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.		NO Synthase , Prostaglandin Receptor
T23480	U-83836E		Others
	U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.		Others
T3999	D(+)-Galactosamine hydrochloride	D-Galactosamine HCl	Others
	D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.		Others
T11855	Lipopolysaccharides	LPS	Others
	Lipopolysaccharides (LPS) is a natural product, an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides are highly immunogenic antigens that enhance the immune res...		Others
T9524	Lanthanum trichloride		Others
	Lanthanum trichloride can be used as an analytical reagent and can be used as a raw material for extracting metal lanthanum and as a petroleum cracking catalyst. Lanthanum chloride also has a certain role in the field of...		Others
T23636	Adenosine N1-oxide	ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide	Immunology/Inflammation related
	Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.		Immunology/Inflammation related
T4S0350	Licochalcone B		Beta Amyloid , Others
	1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...		Beta Amyloid , Others
T68025	Zoliprofen		Others
	Zoliprofen is a potent and orally available non-steroidal anti-inflammatory agent with anti-inflammatory, antipyretic and analgesic activity, and inhibits carobolin, mycobacterium, and knife-ball protein A-induced rat pa...		Others
TN3839	Desoxo-narchinol A		ERK , IL Receptor , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor , JNK
	Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytot...
T29167	XMP-629	XOMA629,XOMA 629,XOMA-629,XMP 629
	XMP-629, an endotoxin inhibitor, is used potentially for the treatment of impetigo and acne rosacea.
T77095	Nebacumab
	Nebacumab (HA-1A), a monoclonal antibody, targets the lipid A component of endotoxin and has potential applications in sepsis research [1] [2].
T71240	AS 703026
	AS 703026 has been shown to inhibit LPS-induced TNFα production in macrophages/monocytes as well as protect from LPS-induced endotoxin shock. AS 703026 may be useful as an anti-inflammatory therapy for COPD patients.
T70874	Vipoglanstat
	Vipoglanstat is a prostaglandin E synthase inhibitor and an anti-inflammatory. Vipoglanstat ameliorates leukocyte infiltration and lung injury resulting from both endotoxin-induced and sepsis-induced lung injury.
T82505	Edobacomab	XMMEN-0E5,E5
	Edobacomab (E5), a monoclonal IgM antibody targeting endotoxin, is utilized in the study of sepsis stemming from Gram-negative bacterial infections [1].
TN3366	Ailanthoidol		IL Receptor , NOS , COX , Prostaglandin Receptor , PPAR
	Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potential as a chemopreventive agent against tumor promotion. Ailan...		IL Receptor , NOS , COX , Prostaglandin Receptor , PPAR