deficit — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4330	CaCCinh-A01		Chloride channel
	CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).		Chloride channel
TQ0046	Bavisant	JNJ-31001074	Histamine Receptor
	Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.		Histamine Receptor
T2150	Guanfacine hydrochloride	Tenex,Intuniv,Guanfacine	Adrenergic Receptor
	Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.		Adrenergic Receptor
T1180	Blonanserin	AD-5423	Dopamine Receptor , Sigma receptor , 5-HT Receptor , Adrenergic Receptor
	Blonanserin (AD-5423) is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerability profile, lacking side effects such as extrapyramidal ...
T12352L	Oxidopamine hydrobromide	6-Hydroxydopamine hydrobromide,6-OHDA hydrobromide	Mitophagy , Dopamine Receptor , Autophagy
	Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.		Mitophagy , Dopamine Receptor , Autophagy
T12352	Oxidopamine hydrochloride	6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride	Mitophagy , Dopamine Receptor , Autophagy
	Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.		Mitophagy , Dopamine Receptor , Autophagy
T7070	Nomifensine maleate	Nomifensine (maleate),(±)-Nomifensine maleat	Dopamine Receptor
	Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.		Dopamine Receptor
T10052	AR-08		Adrenergic Receptor
	AR-08 is a potent α2-adrenergic receptor agonist for the study of ADHD and attention deficit.		Adrenergic Receptor
T60201	CX717		GluR
	CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect. CX 717 can be used for the research of adult attention deficit hyperactivity disorder (ADHD) [1] [2].		GluR
T12054L	MK-0249 FA	MK-0249 FA(862309-06-6 Free base)	Histamine Receptor
	MK-0249 FA is an orally active, selective and potent histamine H3 inverse agonist for the study of attention deficit, hyperactivity disorder neurodivergent and cognitive disorders in adults.		Histamine Receptor
T24857	TBTC
	TBTC is a selective agonist of retinoid X receptor α that acts by improving behavioral deficit in Alzheimer's disease model mice.
T26529	ABT-418	ABT 418,ABT418,A 81418,A81418,A-81418
	ABT-418, a nicotinic acetylcholine receptor (nAchR) agonist, is used potentially for the treatment of attention deficit disorder.
T10226	Sofiniclin	ABT 894	Others
	Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).		Others
T27976	Manifaxine	BW1555U88,BW-1555U-88,1555U88,1555U-88,GW-320659,GW320659
	Manifaxine, a norepinephrine-dopamine reuptake inhibitor, is used potentially for the treatment of attention deficit.
T61544	Edivoxetine hydrochloride
	Edivoxetine hydrochloride is a highly effective and specialized compound used primarily as a norepinephrine reuptake inhibitor (NERI), indicated for the treatment of depressive disorder and attention-deficit/hyperactivit...
T34752	Samelisant dihydrochloride	SUVN-G3031,SUVN-G 3031,SUVN G3031,SUVN-G3031 HCl
	SUVN-G3031 is a antagonist of histamine H3 receptor with potential for the treatment of cognitive impairment, dementia, attention deficit hyperactivity disorder, epilepsy, sleep disorders, obesity, schizophrenia, eating ...
T31604	Edivoxetine	LY-2216684,LY 2216684,LY2216684
	Edivoxetine( LY2216684) is a selective norepinephrine reuptake inhibitor being developed as a treatment for attention deficit hyperactivity disorder (ADHD) and antidepressants.
T14970	Cipralisant	GT-2331	Others
	Cipralisant is a selective histamine H3 receptor antagonist in vivo, and an agonist in vitro (pKi: 9.9 for histamine H3 receptor; Ki: 0.47 nM for rat histamine H3 receptor). It has the potential for the treatment of atte...		Others
T69595	Ispronicline hemigalactarate
	Ispronicline, also known as AZD3480; TC 1734; TC-0173, and RJR 1734, is a alpha4beta2 nicotinic acetylcholine receptor-selective agonist with cognition-enhancing and neuroprotective properties. Ispronicline is potenti...
T8443L	MCI-225 hydrochloride hydrate	AA-10021,AA10021,MCI225,DDP-225,AA-10025,AA-10026
	MCI-225 is a norepinephrine reuptake/5-HT3/5-HT reuptake inhibitor. MCI-225 could be effective in the treatment of senile dementia of the Alzheimer type, which is accompanied with both deficit in the BF-cortex cholinergi...