Home Tools
Log in
Products Inhibitors Libraries Recombinant Proteins Kits Services Contact Us
Cart
Peptides Monoclonal Antibodies Dye Reagents PROTAC Virtual Screening TargetMol Kits Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails Natural Products Phenols Alkaloids Flavonoids
Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " ciap1 "

Targets

Others

64

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T17870 cIAP1 ligand 1 E3 ligase Ligand 12 Others
cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used to couple with androgen receptor ligands ...
T39609 cIAP1 Ligand-Linker Conjugates 16 cIAP1 Ligand-Linker Conjugates 16
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs.
T69322 cIAP1-IN-D19
cIAP1-IN-D19 is an inhibitor of E3 ligase activity of cIAP1.
T17890 cIAP1 Ligand-Linker Conjugates 2 Hydrochloride E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base) Others
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1].
T17869 cIAP1 ligand 2 E3 ligase Ligand 11 Others
cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
T17893 cIAP1 Ligand-Linker Conjugates 5 E3 ligase Ligand-Linker Conjugates 39 Others
cIAP1 Ligand-Linker Conjugates 5 is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 5, is specifically designed for...
T17894 cIAP1 Ligand-Linker Conjugates 3 E3 ligase Ligand-Linker Conjugates 40 Others
cIAP1 Ligand-Linker Conjugates 3 are chemical compounds comprising an IAP ligand designed specifically for the E3 ubiquitin ligase and a PROTAC linker. These conjugates, denoted as cIAP1 Ligand-Linker Conjugates 3, find ...
T17891 cIAP1 Ligand-Linker Conjugates 2 E3 ligase Ligand-Linker Conjugates 37 Others
cIAP1 Ligand-Linker Conjugates 2 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. This compound is particularly useful in the design of SNIPERs [1].
T17889 cIAP1 Ligand-Linker Conjugates 14 E3 ligase Ligand-Linker Conjugates 36 Others
cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1]...
T17887 cIAP1 Ligand-Linker Conjugates 15 E3 ligase Ligand-Linker Conjugates 34 Others
cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1...
T17896 cIAP1 Ligand-Linker Conjugates 4 E3 ligase Ligand-Linker Conjugates 42 Others
cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potenti...
T17885 cIAP1 Ligand-Linker Conjugates 11 E3 ligase Ligand-Linker Conjugates 33 Others
cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in ...
T17901 cIAP1 Ligand-Linker Conjugates 10 E3 ligase Ligand-Linker Conjugates 47 Others
cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROT...
T17900 cIAP1 Ligand-Linker Conjugates 8 E3 ligase Ligand-Linker Conjugates 46 Others
cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1].
T17884 cIAP1 Ligand-Linker Conjugates 11 Hydrochloride E3 ligase Ligand-Linker Conjugates 33 Hydrochloride Others
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs,...
T17895 cIAP1 Ligand-Linker Conjugates 1 E3 ligase Ligand-Linker Conjugates 41 Others
cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1].
T17892 cIAP1 Ligand-Linker Conjugates 12 E3 ligase Ligand-Linker Conjugates 38 Others
cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creatin...
T17897 cIAP1 Ligand-Linker Conjugates 13 E3 ligase Ligand-Linker Conjugates 43 Others
cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1].
T17899 cIAP1 Ligand-Linker Conjugates 9 E3 ligase Ligand-Linker Conjugates 45 Others
cIAP1 Ligand-Linker Conjugates 9 feature an IAP ligand specifically targeting the E3 ubiquitin ligase, along with a PROTAC linker. It is valuable tools for developing SNIPERs[1].
T17898 cIAP1 Ligand-Linker Conjugates 7 E3 ligase Ligand-Linker Conjugates 44 Others
cIAP1 Ligand-Linker Conjugates 7 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. It is utilized in the design of SNIPERs[1].
T17888 cIAP1 Ligand-Linker Conjugates 6 hydrochloride E3 ligase Ligand-Linker Conjugates 35 hydrochloride Others
cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1].
T17886 cIAP1 Ligand-Linker Conjugates 15 hydrochloride E3 ligase Ligand-Linker Conjugates 34 hydrochloride Others
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
T64302 XIAP/cIAP1 antagonist-1
XIAP/cIAP1 antagonist-1 is a potent, orally active XIAP/cIAP1 antagonist that acts on XIAP (EC50: 5.1 nM) and cIAP1 (EC50: 0.32 nM). xIAP/cIAP1 antagonist-1 dose-dependently inhibits tumour growth in vivo.
T13410 ZLDI-8 Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.
T8931L ICCB-19 hydrochloride ICCB-19 HCl（750621-52-4 free base） Apoptosis , Others , Autophagy , RIP kinase
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal dom...
T14378L AZD5582 acetate (1258392-53-8 free base) IAP
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis.
T36201L AZD5582 TFA AZD5582 TFA（1258392-53-8 free base） Apoptosis , IAP
AZD5582 TFA is a potent IAP antagonist that binds to the BIR3 domain of cIAP1, cIAP2, and XIAP with IC50 values of 15, 21, and 15 nM, respectively.AZD5582 TFA induces apoptosis.
T6763 Xevinapant ARRY-334543,SM-406,AT406,Debio-1143 IAP
Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, ...
T2080 LCL161 IAP
LCL161, a SMAC mimetic, effectivity binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP).
T6299 GDC-0152 GDC0152 IAP
GDC-0152 is a potent inhibitor of IAPs.
T6007 Birinapant TL32711 Apoptosis , IAP , HIV Protease
Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with po...
T12932L SM-164 Apoptosis , IAP
SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.
T36201 AZD5582 dihydrochloride AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to ...
T14378 AZD5582 Apoptosis , IAP
AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.
T23760 AT-IAP
AT-IAP is an effective dual antagonist of XIAP and cIAP1.
T17545 Biotin-BS Others
Biotin-BS is a chemical compound composed of two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and biotin. These ligands are interconnected through linkers. MeBS serves as a ligand specifically for the cellular inhi...
T17706 BzNH-BS Others
BzNH-BS is a chemical compound comprising two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide. The ligands are interconnected through linkers. MeBS functions as a ligand for cIAP1, a ubiquitin ligase...
T69845 MX107
MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.
T18690 SNIPER(ABL)-039 Others
SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 nM. IC50s are 0.54 nM, 10 nM, 12 nM, and 50 nM for ABL, c...
T18635 PROTAC RAR Degrader-1 Others
PROTAC RAR Degrader-1, an RAR degrader, consists of a cIAP1 ligand binding group, a linker, and an RAR ligand binding group. It achieves maximal RAR degradation at a concentration of 30 μM in HT1080 cells. Degradation in...
T18596 PROTAC AR Degrader-4 Others
PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-g...
T16905 SNIPER(BRD)-1 Others
SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway an...
T69840 MX106
MX106 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.
T78947 CST626 PROTACs
CST626 (Compound 9), a pan-IAP degrader PROTAC, effectively degrades XIAP, cIAP1, and cIAP2 in MM.1S cells with DC50 values of 0.7, 2.4, and 6.2 nM, respectively [1].
T18605 PROTAC ERα Degrader-2 Others
PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader. It achieves maximal ERα degradation in human mammary tumor MCF7 cel...
T3299 Xevinapant hydrochloride AT-406 HCl,SM-406 Apoptosis , IAP
Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66....
T13837 PROTAC CRABP-II Degrader-2 Others
PROTAC CRABP-II Degrader-2 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1.
T13838 PROTAC CRABP-II Degrader-3 Others
PROTAC CRABP-II Degrader-3 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1.
T13836 PROTAC CRABP-II Degrader-1 Others
PROTAC CRABP-II Degrader-1 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1.
T14288 Androstanolone acetate Others
Androstanolone acetate is a compound that functions as an androgen ligand, specifically targeting the androgen receptor (AR). It binds to the cIAP1 ligand Bestatin through a linker, resulting in the formation of PROTACs[...

Compounds

cIAP1 ligand 1
T17870
Synonym: E3 ligase Ligand 12
Target: Others
cIAP1 Ligand-Linker Conjugates 16
T39609
Synonym: cIAP1 Ligand-Linker Conjugates 16
Target:
cIAP1-IN-D19
T69322
Synonym:
Target:
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride
T17890
Synonym: E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base)
Target: Others
cIAP1 ligand 2
T17869
Synonym: E3 ligase Ligand 11
Target: Others
cIAP1 Ligand-Linker Conjugates 5
T17893
Synonym: E3 ligase Ligand-Linker Conjugates 39
Target: Others
cIAP1 Ligand-Linker Conjugates 3
T17894
Synonym: E3 ligase Ligand-Linker Conjugates 40
Target: Others
cIAP1 Ligand-Linker Conjugates 2
T17891
Synonym: E3 ligase Ligand-Linker Conjugates 37
Target: Others
cIAP1 Ligand-Linker Conjugates 14
T17889
Synonym: E3 ligase Ligand-Linker Conjugates 36
Target: Others
cIAP1 Ligand-Linker Conjugates 15
T17887
Synonym: E3 ligase Ligand-Linker Conjugates 34
Target: Others
cIAP1 Ligand-Linker Conjugates 4
T17896
Synonym: E3 ligase Ligand-Linker Conjugates 42
Target: Others
cIAP1 Ligand-Linker Conjugates 11
T17885
Synonym: E3 ligase Ligand-Linker Conjugates 33
Target: Others
cIAP1 Ligand-Linker Conjugates 10
T17901
Synonym: E3 ligase Ligand-Linker Conjugates 47
Target: Others
cIAP1 Ligand-Linker Conjugates 8
T17900
Synonym: E3 ligase Ligand-Linker Conjugates 46
Target: Others
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride
T17884
Synonym: E3 ligase Ligand-Linker Conjugates 33 Hydrochloride
Target: Others
cIAP1 Ligand-Linker Conjugates 1
T17895
Synonym: E3 ligase Ligand-Linker Conjugates 41
Target: Others
cIAP1 Ligand-Linker Conjugates 12
T17892
Synonym: E3 ligase Ligand-Linker Conjugates 38
Target: Others
cIAP1 Ligand-Linker Conjugates 13
T17897
Synonym: E3 ligase Ligand-Linker Conjugates 43
Target: Others
cIAP1 Ligand-Linker Conjugates 9
T17899
Synonym: E3 ligase Ligand-Linker Conjugates 45
Target: Others
cIAP1 Ligand-Linker Conjugates 7
T17898
Synonym: E3 ligase Ligand-Linker Conjugates 44
Target: Others
cIAP1 Ligand-Linker Conjugates 6 hydrochloride
T17888
Synonym: E3 ligase Ligand-Linker Conjugates 35 hydrochloride
Target: Others
cIAP1 Ligand-Linker Conjugates 15 hydrochloride
T17886
Synonym: E3 ligase Ligand-Linker Conjugates 34 hydrochloride
Target: Others
XIAP/cIAP1 antagonist-1
T64302
Synonym:
Target:
ZLDI-8
T13410
Synonym:
Target: Apoptosis, Phosphatase, Gamma-secretase, Immunology/Inflammation related
ICCB-19 hydrochloride
T8931L
Synonym: ICCB-19 HCl（750621-52-4 free base）
Target: Apoptosis, Others, Autophagy, RIP kinase
AZD5582 acetate (1258392-53-8 free base)
T14378L
Synonym:
Target: IAP
AZD5582 TFA
T36201L
Synonym: AZD5582 TFA（1258392-53-8 free base）
Target: Apoptosis, IAP
Xevinapant
T6763
Synonym: ARRY-334543,SM-406,AT406,Debio-1143
Target: IAP
LCL161
T2080
Synonym:
Target: IAP
GDC-0152
T6299
Synonym: GDC0152
Target: IAP
Birinapant
T6007
Synonym: TL32711
Target: Apoptosis, IAP, HIV Protease
SM-164
T12932L
Synonym:
Target: Apoptosis, IAP
AZD5582 dihydrochloride
T36201
Synonym: AZD 5582 dihydrochloride
Target:
AZD5582
T14378
Synonym:
Target: Apoptosis, IAP
AT-IAP
T23760
Synonym:
Target:
Biotin-BS
T17545
Synonym:
Target: Others
BzNH-BS
T17706
Synonym:
Target: Others
MX107
T69845
Synonym:
Target:
SNIPER(ABL)-039
T18690
Synonym:
Target: Others
PROTAC RAR Degrader-1
T18635
Synonym:
Target: Others
PROTAC AR Degrader-4
T18596
Synonym:
Target: Others
SNIPER(BRD)-1
T16905
Synonym:
Target: Others
MX106
T69840
Synonym:
Target:
CST626
T78947
Synonym:
Target: PROTACs
PROTAC ERα Degrader-2
T18605
Synonym:
Target: Others
Xevinapant hydrochloride
T3299
Synonym: AT-406 HCl,SM-406
Target: Apoptosis, IAP
PROTAC CRABP-II Degrader-2
T13837
Synonym:
Target: Others
PROTAC CRABP-II Degrader-3
T13838
Synonym:
Target: Others
PROTAC CRABP-II Degrader-1
T13836
Synonym:
Target: Others
Androstanolone acetate
T14288
Synonym:
Target: Others
1 2

Recombinant Proteins

Species：
Human (1)
Expression System：
E. coli (1)
Tag：
Avi (1)
Cat No. Product Name Species Expression System
TMPY-01176 cIAP1 Protein, Human, Recombinant (Avi) Human E. coli
The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r...
CORPORATE
About Us Careers Privacy Notice Events & News Terms & Conditions
SUPPORT
Contact Us Worldwide Distributors Quality Control Technical Support
RESOURCE
Product Catalog Product Citations Signaling Pathways Solution Calculators
FOLLOW OUR
Social Network
Newsletter Subscription
Subscribe to receive our lastest product updates and special offers!
Corporate
Support
Resource
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
TargetMol
Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.