apoptosis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1772	MDK83190	Apoptosis Activator 2	Apoptosis , Caspase
	MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .		Apoptosis , Caspase
T3293	Apoptozole	Apoptosis Activator VII	Apoptosis , HSP
	Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.		Apoptosis , HSP
T30102	Apoptosis inducer 5d
	Apoptosis inducer 5D is a new type of inducer that induces cell death by activating the apoptosis of cancer cells.
T63232	Apoptosis inducer 6
	Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.
T74787	Apoptosis inducer 12
	Apoptosis Inducer 12 (Compound 3z) is a compound that promotes cell death via the mitochondrial pathway and is utilized in cancer research [1].
T72509	Apoptosis inducer 5
	Apoptosis Inducer 5, a lignan enantiomer extracted from Crataegus pinnatifida, demonstrates cytotoxic properties through inducing apoptosis and autophagy in Hep3B cells.
T78686	Apoptosis inducer 11		Apoptosis
	Apoptosis Inducer 11 (compound 3u) promotes apoptosis via the mitochondrial pathway and elicits a G2/M block alongside a marked reduction in the S phase within non-Hodgkin lymphoma cell lines [1].		Apoptosis
T79252	Apoptosis inducer 13		Reactive Oxygen Species
	Apoptosis Inducer 13 (Compound Ru4) promotes apoptosis in cancer cells while also suppressing their migration and invasion. Additionally, it facilitates the conversion of coenzyme NADH to NAD+, and elevates intracellular...		Reactive Oxygen Species
T62399	Apoptosis inducer 10
	Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity. apoptosis inducer 10 induces apoptosis in HeLa cancer cells using a mitochondria-dependent endogenous pathway.
T74490	Apoptosis inducer 3
	Apoptosis Inducer 3 (Compound 3), a selective apoptosis triggering agent, induces both apoptosis and late-apoptosis phases, demonstrating cytotoxic effects against cancer cells [1].
T74493	Apoptosis inducer 4
	Apoptosis Inducer 4 (Compound 12b) is a compound that induces apoptosis and exhibits anticancer properties [1].
T63485	Apoptosis inducer 8
	Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used in major lung cancer studies worldwide.
T4371	CD437	AHPN,O-Desmethyl Adapalene,Apoptosis Activator VI	Retinoid Receptor , Autophagy
	CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.		Retinoid Receptor , Autophagy
T23189	Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]		Others
	Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.		Others
TN1065	Hirsutine		Apoptosis
	Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation acti...		Apoptosis
T3390	Obacunone		Apoptosis , Aromatase , p38 MAPK
	Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typh...		Apoptosis , Aromatase , p38 MAPK
T14973	CITCO		Apoptosis , Others
	CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it al...		Apoptosis , Others
T10619	Bromelain		Apoptosis , Others
	Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression,...		Apoptosis , Others
T5S1897	Linderalactone		Apoptosis , Others , JAK
	1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.		Apoptosis , Others , JAK
TN1038	Galgravin		Apoptosis
	Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec...		Apoptosis