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Obacunone

Catalog No. T3390 CAS 751-03-1

Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.

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Obacunone, CAS 751-03-1

Pack Size	Availability	Price/USD	Quantity
20 mg	In stock	$ 100.00
1 mL * 10 mM (in DMSO)	In stock	$ 60.00

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Purity: 99.92%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.
Targets&IC50	Aromatase:28.4 μM
Source	Natural Products > Rutaceae > Phellodendron

Molecular Weight	454.51
Formula	C26H30O7
CAS No.	751-03-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 82 mg/mL(180.4 mM)

References and Literature

1. Murthy KN, et al.Toxicology. 2015 Mar 2;329:88-97. 2. Kim J, et al. Biochimie. 2014 Oct;105:36-44. 3. Vikram A, et al. Appl Environ Microbiol. 2012 Oct;78(19):72012-22.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Kinase Inhibitor Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Active Compound Library Anti-Infection Compound Library Anti-Obesity Compound Library Immunology/Inflammation Compound Library Anti-Pancreatic Cancer Compound Library Oxidation-Reduction Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library

Related Products

Related compounds with same targets

3-O-Methylgallic acid Trigonelline WHI-P154 BRD3308 (1E,6E)-Bis(demethoxy)curcumin (Rac)-Idroxioleic acid BTdCPU GSK-923295

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Obacunone 751-03-1 Apoptosis Endocrinology/Hormones MAPK p38 MAPK Aromatase Inhibitor inhibit inhibitor

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