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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10140 | 4-Diethylaminobenzaldehyde | Dehydrogenase | |
4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71μM). | |||
T7957 | 2-Isopropyl Thioxanthone | Others | |
2-Isopropyl Thioxanthone has potential anti-estrogenic and anti-androgenic properties. | |||
T14843 | Bifluranol | BX341 | Androgen Receptor |
Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH). | |||
T30161 | EN3356 | AS N001,ASN-001 | P450 |
EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and ant... | |||
T1284 | Megestrol acetate | SC10363,BDH1298 | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , HIV Protease , Autophagy |
Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment ... | |||
T25961 | Piperophos | Rilof | |
Piperophos is an organophosphate with anti-androgenic activities. | |||
T73671 | 7β-Hydroxy-epi-androsterone | ||
7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) is an endogenous androgenic derivative of dehydroepiandrosterone that possesses the ability to bind to ERβ, offering both anti-inflammatory and neuroprotective properties [1]... | |||
T81662 | N-Nitrosodicyclohexylamine | NDCHA | Androgen Receptor |
N-Nitrosodicyclohexylamine (NDCHA), an N-nitrosocompound, exhibits anti-androgenic activity by competitively binding to the androgen receptor (AR) in opposition to 5α-dihydrotestosterone and reducing AR protein levels [1... | |||
TN4604 | Myricanone | BCL , HSP , NF-κB , ROS , Caspase , STAT | |
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-κB and STAT3 signalling cascades... |