a-naphthoquinone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7048	1,4-Naphthoquinone	α-Naphthoquinone,Naphthalene-1,4-Dione,P-Naphthoquinone,para-naphthoquinone	Others , MAO , Topoisomerase
	1,4-Naphthoquinone (P-Naphthoquinone) was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase activity[1].		Others , MAO , Topoisomerase
T7075	2-Chloronaphthoquinone	2-Chloro-1,4-naphthoquinone	Others
	2-Chloronaphthoquinone (2-Chloro-1,4-naphthoquinone) is a substituted naphthoquinone which is used as an insecticide and acaricide.		Others
T5S2350	Beta-Acetoxyisovalerylshikonin	Acetoxyisovalerylalkannin	Others
	Acetoxyisovalerylshikonin, a naphthoquinone derivative extracted from Arnebia euchroma, is a chemical compound.		Others
T16706	Quinoclamine		NF-κB
	Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.		NF-κB
T0449	Menadione	Vitamin K3	Thrombin , Endogenous Metabolite
	Menadione (Vitamin K3) is a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.		Thrombin , Endogenous Metabolite
T5426	DMNQ		Reactive Oxygen Species , ROS
	DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS generation		Reactive Oxygen Species , ROS
T2969	Lawsone	Hennotannic acid,2-hydroxy-1,4-naphthoquinone	Others , Antifungal
	Lawsone (Hennotannic acid) (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichh...		Others , Antifungal
T2841	Plumbagin	Plumbagone,Plumbagine,Plumbaein,2-Methyljuglone	ROS
	Plumbagin (Plumbaein) is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. It is also commonly found in the carnivorous plant genera Dr...		ROS
T2897	(Rac)-Shikonin	(±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid	Others
	(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,...		Others
T4958	(-)-Alkannin	Alkannin,Shikonin	Apoptosis , PI3K
	(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a...		Apoptosis , PI3K
T4010	Juglone	5-Hydroxy-1,4-naphthoquinone,Regianin	DNA/RNA Synthesis , Antibacterial
	Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin fam...		DNA/RNA Synthesis , Antibacterial
T36914	2-Hydroxyanthraquinone		Others
	2-Hydroxyanthraquinone is an anthraquinone that has been found inSpermacoce latifoliaand has antibacterial and estrogenic activities.1,2It is active againstB. subtilisandB. cereus(MICs = 1.9 and 62.5 μg/ml, respectively)...		Others
T29792	AK-135
	AK-135 is a derivative of 1,4-naphthoquinone (Menadione). AK-135 has been shown to restore the electron flow in defective respiratory chain (hypoxia or rotenone) systems more effectively than Menadione.
TN5790	2-Carbamoyl-3-hydroxy-1,4-naphthoquinone
	2-Carbamoyl-3-hydroxy-1,4-naphthoquinone is a natural product for research related to life sciences. The catalog number is TN5790 and the CAS number is 103646-20-4.
TN1208	2-Amino-3-carboxy-1,4-naphthoquinone		NADPH-oxidase
	2-Amino-3-carboxy-1,4-naphthoquinone is the electron transfer mediator, can change glucose metabolism of the homofermentative lactic acid bacteria. 2-Amino-3-carboxy-1,4-naphthoquinone is a novel growth stimulator for bi...		NADPH-oxidase
T26450	A 80915A	A80915A,A-80915A
	A 80915A is A semi-naphthoquinone antibiotic from Streptomyces aculeolatus. It is a potent inhibitor of gastric (H(+)-K+)-ATPase. Inhibition by A80915A is dependent on the conformation of gastric (H(+)-K+)-ATPase, potass...
T36207	Methylspinazarin
	Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml).1 It is selective for COMT over tyrosine hydroxyl...
T83877	2-(cyclohexylmethyl)-Plumbagin
	2-(Cyclohexylmethyl)-Plumbagin, a naphthoquinone derivative, exhibits selective cytotoxicity towards PANC-1 human pancreatic cancer cells under nutrient-deprived conditions—a situation akin to the pancreatic cancer tumor...
T36645	CAY10763	CAY10763
	CAY10763 is a dual inhibitor of indolamine 2,3-dioxygenase 1 (IDO1; IC50= 46 nM) and STAT3 activation.1It binds to STAT3 (Kd= 530 nM) and selectively reduces the levels of STAT3 phosphorylated at the tyrosine in position...