uti — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7777	M4284	M 4284	Antibacterial
	M4284 (M 4284) is a selective and orally active biphenyl mannoside FimH antagonist.		Antibacterial
T1313	Nitrofurantoin	Furadantine,Macrodantin,Furadonine	Antibacterial , Antibiotic
	Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi...		Antibacterial , Antibiotic
T8139	Sulfamethoxazole sodium	Ro 4-2130 sodium	Others , Antibacterial , Antibiotic
	Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic		Others , Antibacterial , Antibiotic
T8636	Ibrutinib deacryloylpiperidine	IBT4A,5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine	BTK
	Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.		BTK
T7175	Alflutinib mesylate	AST2818 mesylate	EGFR
	Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.		EGFR
TP1796	Albiglutide TFA (782500-75-8 free base)	Albiglutide TFA	Glucagon Receptor
	Albiglutide TFA (782500-75-8 free base) (Albiglutide TFA) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM).		Glucagon Receptor
T5407	Branebrutinib	BMS986195	BTK
	Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family (IC50 <1 nM for BTK).		BTK
T8460	Olmutinib	HM61713,BI1482694	EGFR
	Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor		EGFR
T78097L	Mazdutide acetate（2259884-03-0 free base）	Mazdutide acetate（2259884-03-0 free base）,OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate	Glucagon Receptor
	Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, an...		Glucagon Receptor
TP1472	Tyroserleutide		Others
	Tyroserleutide (YSL), isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo.Tyroserleutide inhibits the growth and metastasis of h...		Others
T19898	Methylarbutin	ß-PMP-Glc;4-Methoxyphenyl β-D-Glucopyranoside,ß-PMP-Glc,4-Methoxyphenyl β-D-Glucopyranoside	Others
	Methylarbutin (ß-PMP-Glc;4-Methoxyphenyl β-D-Glucopyranoside) is an ice recrystallization inhibitor (IRI)		Others
T7618	Pyributicarb	TSH-888	P450
	Pyributicarb (TSH-888) is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR).		P450
T9408	N-piperidine Ibrutinib		BTK
	N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as S...		BTK
T16730	Remibrutinib		BTK
	Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticar...		BTK
T61268	Vutiglabridin	HSG4112	Phosphatase
	Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stabilit...		Phosphatase
T5913	Sulbutiamine	Bisibuthiamine	Antioxidant
	Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.		Antioxidant
TQ0236	Tirabrutinib	ONO-4059,GS-4059,Velexbru	BTK
	Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and ...		BTK
T12542	Rilzabrutinib	PRN1008	EGFR , Others , HER , BTK
	Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK)(IC50 of 1.3 nM).		EGFR , Others , HER , BTK
T12311	Tirabrutinib hydrochloride	ONO-4059 (hydrochloride),GS-4059 (hydrochloride)	BTK
	Tirabrutinib hydrochloride (GS-4059 (hydrochloride)) is a selective and novelBTK with IC50 2.2 nm inhibitor.		BTK
T13447	(R)-Zanubrutinib	(R)-BGB-3111	BTK
	(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).		BTK