Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
5 mg | In stock | $ 233.00 | |
10 mg | In stock | $ 378.00 | |
25 mg | In stock | $ 635.00 | |
50 mg | In stock | $ 885.00 | |
100 mg | In stock | $ 1,230.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 261.00 |
Description | Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment. |
Targets&IC50 | BTK:1 nM |
In vitro | Remibrutinib inhibits Btk enzymatic activity (IC50: 1 nM in a biochemical enzyme assay). Remibrutinib inhibits Btk enzymatic activity in the blood (IC50: 0.023 μM in vitro B cell activation assay), the whole blood is collected from the abdominal aorta of anesthetized adult male Lewis rats[1]. |
Molecular Weight | 507.53 |
Formula | C27H27F2N5O3 |
CAS No. | 1787294-07-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (246.29 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Remibrutinib 1787294-07-8 Angiogenesis Tyrosine Kinase/Adaptors BTK Btk Inhibitor inhibit Bruton tyrosine kinase inhibitor