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Search Results for " thrombin "

20

Compounds

Cat No. Product Name Synonyms Targets
T9845 Thrombin inhibitor 5
Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor with IC 50s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for venous thromboembolism research[1].
T7674 Thrombin Receptor Activator for Peptide Protease-activated Receptor
Thrombin Receptor Activator for Peptide is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).
T19580 Thrombin (MW 37kDa) Thrombin Thrombin
Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.
T10081 Thrombin inhibitor 1 Thrombin
Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).
T7496 Thrombin Receptor Activator for Peptide 5 (TRAP-5) Thrombin Receptor Activator for Peptide Protease-activated Receptor
Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research.
T36777 Thrombin Receptor Agonist Peptide (trifluoroacetate salt)
Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) ...
T17091 Thrombin Inhibitor 2 Others
Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor. Thrombin Inhibitor 2 has antithrombotic activity.
T36553 Thrombin Receptor Peptide Ligand (trifluoroacetate salt)
Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating...
T7625 TRAP-6 PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA) Protease-activated Receptor
TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
T72448 Thrombin inhibitor 6
Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.
TP2234 Coagulation factor II (thrombin) B chain fragment [Homo sapiens] Others
Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser...
T80512 Thrombin receptor peptide ligand Thrombin
Thrombin receptor peptide ligand, a thrombin receptor antagonist, serves as an antithrombotic agent [1].
T3757 NQ301 Thrombin , Platelet aggregation
NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).
T1986L Atopaxar Hydrobromide Protease-activated Receptor
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T1986 Atopaxar E5555,ER-172594-00 Protease-activated Receptor
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T7137 I-191 Protease-activated Receptor
I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.
TQ0012 AZ3451 Protease-activated Receptor
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
T12870 SCH79797 dihydrochloride Apoptosis , Others , Protease-activated Receptor
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects.
T6594 MNS Syk , Src , p97
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
T6295 Dabigatran BIBR 953,BIBR 953ZW Thrombin
Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients...
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