Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 67.00 | |
5 mg | In stock | $ 139.00 | |
10 mg | In stock | $ 255.00 | |
25 mg | In stock | $ 463.00 | |
50 mg | In stock | $ 682.00 | |
100 mg | In stock | $ 969.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 159.00 |
Description | Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. |
Kinase Assay | Kinase assays: WHI-P154 is tested in kinase assays. The panel of kinases is selected to broadly cover the kinome, providing a good approximation of specificity. For all kinases, recombinant rat (IKKβ) or human (all others), full-length or GST-kinase domain fusion proteins, are used. WHI-P154 is inactive (concentration that inhibits response by 50% [IC50] > 30 μM) for the following kinases: AKT, AuroraA, cdk2, cdk6, CHK1, FGFR1, GSK3b, IKKb, IKKi, INSR, MAPK1, MAPKAP-K2, MASK, MET, PAK4, PDK1, PKCb, ROCK1, TaoK3, TrkA. |
Synonyms | E5555, ER-172594-00 |
Molecular Weight | 527.63 |
Formula | C29H38FN3O5 |
CAS No. | 751475-53-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (47.38 mM)
You can also refer to dose conversion for different animals. More
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Atopaxar 751475-53-3 GPCR/G Protein Protease-activated Receptor platelets receptor-1 signaling PAR-1 E5555 inhibit E-5555 Inhibitor receptor Protease Activated Receptor (PAR) protease-activated atherothrombotic thrombin E 5555 Thrombin receptors ER-172594-00 inhibitor