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TRAP-6

Catalog No. T7625 CAS 141136-83-6

Synonyms: PAR-1 agonist peptide, Thrombin Receptor Activator Peptide 6, TRAP-6(2TFA)

TRAP-6(2TFA) is an agonist of protease-activated receptor 1 (PAR1).

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TRAP-6, CAS 141136-83-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	TRAP-6(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
In vitro	For analysis, platelet aggregometry was performed and the influence of epinephrine, adenosine diphosphate, collagen (Coll) and thrombin receptor-activated peptide (TRAP-6) as agonist were determined.?Compared to the control group, patients with venous thromboembolism showed an enhanced maximal platelet aggregation with low concentrations of TRAP-6 (2 microM) and collagen (0.05 microM)[1]

Synonyms	PAR-1 agonist peptide, Thrombin Receptor Activator Peptide 6, TRAP-6(2TFA)
Molecular Weight	748.883
Formula	C34H56N10O9
CAS No.	141136-83-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 33.33 mg/mL (44.51 mM)

DMSO: 28 mg/mL (37.39 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Weber M , Gerdsen F , Gutensohn K , et al. Enhanced platelet aggregation with TRAP-6 and collagen in platelet aggregometry in patients with venous thromboembolism[J]. Thrombosis Research, 2002, 107(6):0-328. 2. De Rossi L W , Horn N A , Hecker K E , et al. Effect of Halothane and Isoflurane on Binding of ADP- and TRAP-6- activated Platelets to Leukocytes in Whole Blood[J]. Anesthesiology, 2002, 96(1):117-124.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Peptide Compound Library Immunology/Inflammation Compound Library Neuronal Signaling Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

SLIGRL-NH2 TRAP-6 PAR-4 Agonist Peptide, amide acetate PAR-4 Agonist Peptide, amide TFLLR-NH2 Thrombin Receptor Activator for Peptide 5 (TRAP-5) Protease-Activated Receptor-4 AC-264613

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TRAP-6 141136-83-6 G蛋白偶联受体 Protease-activated Receptor Inhibitor PAR1 Thrombin Receptor Activator Peptide-6 inhibit TRAP 6 thrombin activating Thrombin Receptor Activator Peptide6 Thrombin Receptor Activator Peptide 6 receptor Thrombin receptors protease Protease Activated Receptor (PAR) platelets PAR-1 agonist peptide TRAP6 TRAP-6(2TFA) inhibitor

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