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Search Results for " trpm2 "

Targets

11

Compounds

2

Natural Products

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10247 Adenosine 5'-diphosphoribose sodium Adenosine 5'-diphosphoribose sodium,ADP ribose sodium Endogenous Metabolite , TRP/TRPV Channel , Autophagy
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a potent ...
T2007 RQ-00203078 TRP/TRPV Channel
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
T16532 Pico145 HC-608 TRP/TRPV Channel
Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits ( )-englerin A-activated TRPC4/TRPC5 channels (IC50s: 0.349 and 1.3 nM in cells) It also shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, T...
T9263 Cim0216 N-(5-methyl-1,2-oxazol-3-yl)-2-phenyl-2-(1,2,3,4-tetrahydroquinolin-1-yl)acetamide TRP/TRPV Channel
CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.
T1622 Rosiglitazone maleate BRL 49653C,BRL 49653 Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
T80506 TAT-M2NX tatM2NX
TAT-M2NX (tatM2NX) is a selective TRPM2 inhibitor that exhibits neuroprotective effects in male mice. It is utilized in research to investigate ischemic neuronal injury [1].
T73755 Farnesyl pyrophosphate
Farnesyl pyrophosphate (Farnesyl diphosphate), a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, acts as a metabolic intermediary. It serves as a TRPM2 (TRP Channel) agonist, facilitating the opening of T...
T78081 Farnesyl Pyrophosphate ammonium Farnesyl diphosphate ammonium
Farnesyl Pyrophosphate Ammonium Salt, a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, functions as a TRPM2 (TRP Channel) agonist, facilitating the opening of TRPM2 channels for ion influx. It serves as ...
T74779 JNJ-28583113
JNJ-28583113, a TRPM2 antagonist with brain permeability, inhibits the phosphorylation of GSK3α and β subunits, thereby protecting cells from oxidative stress-induced cell death. Additionally, it suppresses cytokine rele...
T37475 Cyclic ADP-Ribose (ammonium salt) cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)
Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.[1],[2],[3],[4],[5] This second mes...
T83730 Tat-M2NX TFA
Tat-M2NX, a peptide antagonist of transient receptor potential melastatin 2 (TRPM2), blocks hydrogen peroxide-induced calcium influx in HEK293 cells expressing human TRPM2 at concentrations between 25 to 100 µM. In male ...
Cat No. Product Name Synonyms Targets
T37687 Cyclic ADP-ribose ammonium
Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-med...
T19253 Cyclic ADP-​ribose cADPR Calcium Channel
Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-med...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His) Human HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-06908 Clusterin Protein, Human, Recombinant (sCLU, His) Human HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPJ-00278 Clusterin Protein, Human, Recombinant (hFc & His) Human Human Cells
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic bi...
TMPJ-00279 Clusterin Protein, Human, Recombinant (His) Human Human Cells
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic bi...
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