Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 36.00 | |
50 mg | In stock | $ 52.00 | |
100 mg | In stock | $ 84.00 | |
200 mg | In stock | $ 150.00 | |
500 mg | In stock | $ 249.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 39.00 |
Description | Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. |
Targets&IC50 | PPARγ:42 nM |
In vivo | In numerous cell lines, Rosiglitazone has been found to inhibit cholesterol synthesis. It activates the AMP-activated protein kinase (AMPK) complex, which includes the α1 and α2 subunits within the AMPKα subunit, leading to an increase in phosphorylation. |
Synonyms | BRL 49653C, BRL 49653 |
Molecular Weight | 473.5 |
Formula | C22H23N3O7S |
CAS No. | 155141-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 87 mg/mL (183.9 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Rosiglitazone maleate 155141-29-0 Apoptosis Autophagy DNA Damage/DNA Repair Membrane transporter/Ion channel Metabolism Ferroptosis PPAR TRP/TRPV Channel TRP Channel BRL-49653 BRL 49653C inhibit Transient receptor potential channels Rosiglitazone Maleate Peroxisome proliferator-activated receptors BRL49653 BRL 49653 Inhibitor Rosiglitazone inhibitor