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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2701 | GSK1292263 | GPR | |
GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2. | |||
T9022 | AZD9977 | AZD 9977 | Glucocorticoid Receptor |
AZD9977 is a novel, selective modulator of mineralocorticoid receptor . | |||
T15432 | GSK256073 | GPR , Others | |
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inh... | |||
T12710 | Retagliptin Phosphate | SP 2086 | Proteasome , DPP-4 |
Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes. | |||
T2371 | Emapunil | AC-5216,XBD-173 | Others |
Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. | |||
T1286 | Vincamine | Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval | GPR , Others |
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders. | |||
T8780 | AMG131 | INT-131,AMG-131,CHS 131 | PPAR |
AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende... | |||
TP1796 | Albiglutide TFA (782500-75-8 free base) | Albiglutide TFA | Glucagon Receptor |
Albiglutide TFA (782500-75-8 free base) (Albiglutide TFA) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). | |||
T27439 | GS-9667 | CVT-3619,CVT 3619 | Adenosine Receptor |
GS-9667, a selective and partial agonist of the A(1) adenosine receptor (AR), represents an effective therapy for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA). | |||
T71394 | BMS-823778 | ||
BMS-823778 is an orally available potent and selective inhibitor of 11-β-hydroxysteroid-dehydrogenase 1 (11βHSD-1). BMS-823778 is a potential therapeutic agent for type 2 diabetes mellitus (T2DM). | |||
T77781 | Lotiglipron | PF-07081532 | Glucagon Receptor |
Lotiglipron (PF-07081532) is an orally active and potent GLP-1R agonist that reduces blood glucose and body weight and may be useful in the study of type 2 diabetes mellitus (T2DM) and obesity. | |||
TP1469 | Lixisenatide acetate (320367-13-3 free base) | Lixisenatide acetate | Glucagon Receptor |
Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM). | |||
T27841 | Lobeglitazone Sulfate | CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang | NOD |
Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2... | |||
T67898 | α-Glucosidase-IN-22 | Glucosidase | |
α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies. | |||
T16486 | Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD | PF-05231023 | FGFR , PROTAC Linker |
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM. | |||
T3863 | Chikusetsusaponin IVa | Calenduloside F | AMPK |
Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used... | |||
T6237 | Trelagliptin | SYR-472 | Proteasome , DPP-4 |
Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor. | |||
T4460 | Dapagliflozin ((2S)-1,2-propanediol, hydrate) | BMS-512148 (2S)-1,2-propanediol, hydrate,Dapagliflozin propanediol monohydrate | SGLT |
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the tre... | |||
T2296 | Trelagliptin succinate | SYR-472 succinate,SYR472 | Proteasome , DPP-4 |
Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (T2D). | |||
T15810 | LY2922470 | GPR | |
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava... |