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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11279 | FGFR1/DDR2 inhibitor 1 | Discoidin Domain Receptor (DDR) , FGFR , Others | |
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively. | |||
T11847L | Liarozole | R75251 dihydrochloride | P450 , Retinoid Receptor |
Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 1... | |||
T7417 | Avatrombopag | YM477,AKR-501,E5501 | Thrombin , Thrombopoietin Receptor |
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production. | |||
T3932 | Viscidulin I | Others | |
Viscidulin I is found in Scutellaria baicalensis and is a natural product. | |||
TN2302 | Viscidulin III | Ganhuangenin | Glucosidase |
Viscidulin III (Ganhuangenin) is present in Scutellaria baicalensis and acts as an α-glucosidase inhibitor. | |||
T80378 | Tilapia piscidin 3 | ||
Tilapia piscidin 3, an antimicrobial peptide, exhibits antibacterial properties effective against both gram-positive and gram-negative bacteria. It has demonstrated minimum inhibitory concentrations (MICs) of 2.44 µg/mL ... | |||
T30152 | Ascididemin | Leptoclinidinone,CRL 8274,NSC-675670,NSC 675670,NSC675670 | |
Ascididemin can be regarded as a fused phenanthroline with quinoline. | |||
T124820 | Piscidic acid | ||
Piscidic acid is a useful organic compound for research related to life sciences and the catalog number is T124820. | |||
TN4801 | Piscidinol A | Others | |
Piscidinol A is toxic against the 4T1 and HEp2 cancer cell lines, the IC50 of 8.0 ± 0.03 and 8.4 ± 0.01 uM, respectively. It can inhibit NO production in mouse peritoneal macrophages with inhibitory ratios ranging from 3... | |||
TN5238 | Viscidulin II | IL Receptor , TNF | |
Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of ... | |||
TN5239 | Viscidulin III tetraacetate | Others | |
Viscidulin III tetraacetate is a natural product for research related to life sciences. The catalog number is TN5239 and the CAS number is 96684-81-0. | |||
T11151 | Ecteinascidin-Analog-1 | Others | |
Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues. | |||
T11150 | Ecteinascidin 770 | Ecteinascidine 770,Et-770 | Others |
Ecteinascidin 770 (ET-770) inhibits U373MG cells and is a 1,2,3, 4-tetrahydroisoquinoline alkaloid with strong anticancer activity.IC50 is 4.83 nM. | |||
TP1521 | Piscidin-1 (22-42) (TFA) | ||
Piscidin-1 (22-42) (TFA) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). | |||
T80286 | TP4 (Nile tilapia piscidin) | Necroptosis | |
TP4 (Nile tilapia piscidin) is an orally active piscidin-like antimicrobial peptide that exhibits inhibition of various gram-positive and negative bacterial strains with a minimum inhibitory concentration (MIC) ranging f... | |||
TP1475 | Piscidin-1 (22-42) | ||
Piscidin-1 (22-42) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). | |||
T60248 | 4-Aminobenzamidine dihydrochloride | p-Aminobenzamidine dihydrochloride | Serine Protease |
4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inh... | |||
T36674 | DMU-212 | Apoptosis , ERK | |
DMU-212 is a methylated derivative of Resveratrol , with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2... | |||
T78805 | AD4 | Others | |
AD4, an artemisinin derivative functioning as a proteolytic targeting chimera (PROTAC) for PCLAF, effectively degrades PCLAF in RS4;11 cells with an IC50 of 0.6 nM. This degradation activates the p21/Rb axis, resulting i... | |||
T78305 | Briquilimab | JSP-191 | |
Briquilimab (JSP-191), a non-toxic humanized monoclonal antibody, targets CD117 (c-Kit) to deplete hematopoietic stem cells (HSCs), providing a safe approach for clearing host marrow niche to facilitate adequate donor HS... |