20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23164 | PIT | 2,2'-Pyridylisatogen tosylate | P2Y Receptor |
PIT (2,2'-Pyridylisatogen tosylate) is a specific and non-competitive antagonist of the Purinergic receptor P2Y1 with an IC50 of 0.14 μM for human P2Y1. PIT does not affect nucleotide binding and can be used in studies a... | |||
T23163 | PIT 1 | Others | |
Akt signaling inhibitor | |||
T35491 | 3,5-dimethyl PIT-1 | ||
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is impor... | |||
T68068 | Ezlopitant | CJ 11974,CJ-11974,CJ11974 | Neurokinin receptor |
Ezlopitant (CJ-11974) is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain. | |||
T29096L | Vapitadine | R 129160 | Histamine Receptor |
Vapitadine is a non-sedative antihistamine compound that relieves itching caused by atopic dermatitis. | |||
T25672 | Lesopitron | 5-HT Receptor | |
Lesopitron is an anxiolytic with pre- and postsynaptic 5-HT1A agonist activity and is more effective than 5-HT1A agonists in rat social interaction and marmoset anxiety models. lesopitron counteracts benzodiazepine withd... | |||
T12490 | Pitavastatin lactone | Others | |
Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes. | |||
T2S1086 | Nepitrin | Nepetin-7-glucoside | Antioxidant |
1. Nepitrin (Nepetin-7-glucoside) has antioxidant activity in human HL6 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation. | |||
T1916 | Apitolisib | RG 7422,GNE 390,GDC-0980 | Apoptosis , PI3K , mTOR |
Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kα(IC50=5 nM), PI3Kβ(IC50=27 nM), PI3Kδ(IC50=7 nM), PI3Kγ (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal ce... | |||
T4466 | Pitofenone hydrochloride | Baralgin Ketone Hydrochloride,Pitophenone hydrochloride | AChE |
Pitofenone hydrochloride (Pitophenone hydrochloride), a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively. | |||
T17156 | Tradipitant | VLY-686,LY686017 | Neurokinin receptor |
Tradipitant (VLY-686) is an antagonist of neurokinin-1. | |||
T14524 | Befetupitant | Ro67-5930 | Neurokinin receptor |
Befetupitant (Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization. | |||
T13329 | Vofopitant | GR 205171 | Neurokinin receptor |
Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD). | |||
T6905 | Netupitant | Ro 67-31898/000,CID 6451149 | Neurokinin receptor |
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM). | |||
TP2189L | V5 Epitope Tag Peptide acetate | Others | |
V5 Epitope Tag Peptide acetate is a peptide | |||
T13131 | Tert-Buthyl Pitavastatin | HMG-CoA Reductase | |
tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase. | |||
T7209 | Maropitant | Neurokinin receptor | |
Maropitant is a selective neurokinin (NK1) receptor antagonist. | |||
T25615 | Lanepitant | LY303870,LY-303870,LY 303870 | Others |
Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine. | |||
T29096 | Vapitadine dihydrochloride | Vapitadine 2HCl,R129160,R-129160 2HCl,Vapitadine HCl,R 129160 2HCl,R-129160,R 129160,R129160 2HCl | Histamine Receptor |
Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1. | |||
T8439 | Clobenpropit dihydrobromide | Apoptosis , Histamine Receptor | |
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07) |