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Search Results for " pit "

20

Compounds

Cat No. Product Name Synonyms Targets
T23164 PIT 2,2'-Pyridylisatogen tosylate P2Y Receptor
PIT (2,2'-Pyridylisatogen tosylate) is a specific and non-competitive antagonist of the Purinergic receptor P2Y1 with an IC50 of 0.14 μM for human P2Y1. PIT does not affect nucleotide binding and can be used in studies a...
T23163 PIT 1 Others
Akt signaling inhibitor
T35491 3,5-dimethyl PIT-1
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is impor...
T68068 Ezlopitant CJ 11974,CJ-11974,CJ11974 Neurokinin receptor
Ezlopitant (CJ-11974) is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain.
T29096L Vapitadine R 129160 Histamine Receptor
Vapitadine is a non-sedative antihistamine compound that relieves itching caused by atopic dermatitis.
T25672 Lesopitron 5-HT Receptor
Lesopitron is an anxiolytic with pre- and postsynaptic 5-HT1A agonist activity and is more effective than 5-HT1A agonists in rat social interaction and marmoset anxiety models. lesopitron counteracts benzodiazepine withd...
T12490 Pitavastatin lactone Others
Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.
T2S1086 Nepitrin Nepetin-7-glucoside Antioxidant
1. Nepitrin (Nepetin-7-glucoside) has antioxidant activity in human HL6 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation.
T1916 Apitolisib RG 7422,GNE 390,GDC-0980 Apoptosis , PI3K , mTOR
Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kα(IC50=5 nM), PI3Kβ(IC50=27 nM), PI3Kδ(IC50=7 nM), PI3Kγ (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal ce...
T4466 Pitofenone hydrochloride Baralgin Ketone Hydrochloride,Pitophenone hydrochloride AChE
Pitofenone hydrochloride (Pitophenone hydrochloride), a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.
T17156 Tradipitant VLY-686,LY686017 Neurokinin receptor
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
T14524 Befetupitant Ro67-5930 Neurokinin receptor
Befetupitant (Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization.
T13329 Vofopitant GR 205171 Neurokinin receptor
Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).
T6905 Netupitant Ro 67-31898/000,CID 6451149 Neurokinin receptor
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
TP2189L V5 Epitope Tag Peptide acetate Others
V5 Epitope Tag Peptide acetate is a peptide
T13131 Tert-Buthyl Pitavastatin HMG-CoA Reductase
tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase.
T7209 Maropitant Neurokinin receptor
Maropitant is a selective neurokinin (NK1) receptor antagonist.
T25615 Lanepitant LY303870,LY-303870,LY 303870 Others
Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.
T29096 Vapitadine dihydrochloride Vapitadine 2HCl,R129160,R-129160 2HCl,Vapitadine HCl,R 129160 2HCl,R-129160,R 129160,R129160 2HCl Histamine Receptor
Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.
T8439 Clobenpropit dihydrobromide Apoptosis , Histamine Receptor
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)
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TargetMol