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Search Results for " pcaf "

20

Compounds

Cat No. Product Name Synonyms Targets
T60762 PCAF-IN-1
PCAF-IN-1 is a antitumor agents used in tumor treatment research. PCAF-IN-1 is a highly selective inhibitor of PCAF [1].
T60452 PCAF-IN-2
PCAF-IN-2 (compound 17) is a potent inhibitor of PCAF with an IC50 of 5.31 µM. PCAF-IN-2 exhibits anti-tumor activity. CAF-IN-2 induces cell apoptosis and arrest the cell cycle at the G2/M phase[1].
T11366 Garcinol Apoptosis , Endogenous Metabolite , Histone Acetyltransferase , AChR , AChE
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone...
T60558 NSC 694623 Histone Acetyltransferase
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with IC50 of 15.9 μM against recombinant HAT p300/CBP associated factor (PCAF). NSC 694623 shows anti-proliferative activity against some cancer cells, whi...
T5468 YF-2 Others , Epigenetic Reader Domain , Histone Acetyltransferase
YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 μM, 29.04 μM and 49.31 μM , respectively
T28471 PU139 PU 139,PU-139 Histone Acetyltransferase
PU139 is a novel inhibitor of histone acetyltransferase (HAT).
T6389 Anacardic Acid 6-pentadecylsalicylic Acid,Hydroginkgolic acid Others , Epigenetic Reader Domain , Histone Acetyltransferase , Antibacterial
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostagland...
T11495L GSK 4027 Others
GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.
T10604 BRD-IN-3 Others
BRD-IN-3 is a highly potent PCAF bromodomain (BRD) inhibitor (IC50: 7 nM). It also exhibits activity against GCN5 and FALZ.
T11495 GSK4028 Others
GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe. The pIC50 of GSK4028 is 4.9 in a TR-FRET assay.
T11807 L002 Others , Histone Acetyltransferase , STAT
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By ...
T71724 F2276-0099
F2276-0099 is a PCAF/GCN5 BRD inhibitor
T71721 F2276-0106
F2276-0106 is a PCAF/GCN5 BRD inhibitor
T71720 F2276-0104
F2276-0104 is a PCAF/GCN5 BRD inhibitor
T23745 APA-APA-MPO APA APA MPO,APAAPAMPO
APA-APA-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.
T23746 APA-H-MPO APAHMPO
APA-H-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.
T25215 CCT077791 CCT 077791,CCT-077791 Epigenetic Reader Domain , Histone Acetyltransferase
CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research.
T71723 F2276-0008
F2276-0008 is a PCAF/GCN5 BRD inhibitor.
T32010 GSK699 GSK-699,GSK 699
GSK699 is a potent, cell penetrant PCAF/GCN5 PROTAC.
T38711 YF-2 hydrochloride
YF-2 hydrochloride is a potent histone acetyltransferase activator that exhibits high selectivity and can pass through the blood-brain barrier. It specifically acetylates H3 in the hippocampus, with EC50 values of 2.75 μ...
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