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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60762 | PCAF-IN-1 | ||
PCAF-IN-1 is a antitumor agents used in tumor treatment research. PCAF-IN-1 is a highly selective inhibitor of PCAF [1]. | |||
T60452 | PCAF-IN-2 | ||
PCAF-IN-2 (compound 17) is a potent inhibitor of PCAF with an IC50 of 5.31 µM. PCAF-IN-2 exhibits anti-tumor activity. CAF-IN-2 induces cell apoptosis and arrest the cell cycle at the G2/M phase[1]. | |||
T11366 | Garcinol | Apoptosis , Endogenous Metabolite , Histone Acetyltransferase , AChR , AChE | |
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone... | |||
T60558 | NSC 694623 | Histone Acetyltransferase | |
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with IC50 of 15.9 μM against recombinant HAT p300/CBP associated factor (PCAF). NSC 694623 shows anti-proliferative activity against some cancer cells, whi... | |||
T5468 | YF-2 | Others , Epigenetic Reader Domain , Histone Acetyltransferase | |
YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 μM, 29.04 μM and 49.31 μM , respectively | |||
T28471 | PU139 | PU 139,PU-139 | Histone Acetyltransferase |
PU139 is a novel inhibitor of histone acetyltransferase (HAT). | |||
T6389 | Anacardic Acid | 6-pentadecylsalicylic Acid,Hydroginkgolic acid | Others , Epigenetic Reader Domain , Histone Acetyltransferase , Antibacterial |
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostagland... | |||
T11495L | GSK 4027 | Others | |
GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF. | |||
T10604 | BRD-IN-3 | Others | |
BRD-IN-3 is a highly potent PCAF bromodomain (BRD) inhibitor (IC50: 7 nM). It also exhibits activity against GCN5 and FALZ. | |||
T11495 | GSK4028 | Others | |
GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe. The pIC50 of GSK4028 is 4.9 in a TR-FRET assay. | |||
T11807 | L002 | Others , Histone Acetyltransferase , STAT | |
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By ... | |||
T71724 | F2276-0099 | ||
F2276-0099 is a PCAF/GCN5 BRD inhibitor | |||
T71721 | F2276-0106 | ||
F2276-0106 is a PCAF/GCN5 BRD inhibitor | |||
T71720 | F2276-0104 | ||
F2276-0104 is a PCAF/GCN5 BRD inhibitor | |||
T23745 | APA-APA-MPO | APA APA MPO,APAAPAMPO | |
APA-APA-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor. | |||
T23746 | APA-H-MPO | APAHMPO | |
APA-H-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor. | |||
T25215 | CCT077791 | CCT 077791,CCT-077791 | Epigenetic Reader Domain , Histone Acetyltransferase |
CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research. | |||
T71723 | F2276-0008 | ||
F2276-0008 is a PCAF/GCN5 BRD inhibitor. | |||
T32010 | GSK699 | GSK-699,GSK 699 | |
GSK699 is a potent, cell penetrant PCAF/GCN5 PROTAC. | |||
T38711 | YF-2 hydrochloride | ||
YF-2 hydrochloride is a potent histone acetyltransferase activator that exhibits high selectivity and can pass through the blood-brain barrier. It specifically acetylates H3 in the hippocampus, with EC50 values of 2.75 μ... |