p-388 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3020	Sclareol		Apoptosis , Others
	Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines.		Apoptosis , Others
TN3669	Cis-N-Feruloyltyramine		Prostaglandin Receptor
	Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line. Cis-N-Feruloyltyramine is an inhibitor of in vitro prostaglandin (PG) synthesi...		Prostaglandin Receptor
TN4147	Glyasperin A		Others
	Glyasperin A has cytotoxic properties against P-388 cells, its IC50 values being 6.0 microM.		Others
TN4376	Kanshone A		Others
	Kanshone A shows cytotoxic activity against P-388 cells.		Others
TN3785	Debilon		Others
	Debilon shows cytotoxic activity against P-388 cells.		Others
TN1628	Eupalinilide B		Others
	Eupalinilides B demonstrates potent cytotoxicity against P-388 and A-549 tumor cell lines.		Others
TN3839	Desoxo-narchinol A		ERK , IL Receptor , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor , JNK
	Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytot...
TN1173	1-Hydroxyrutaecarpine		Others
	1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro.		Others
TN3445	Aristolactam BIII		PAFR
	Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, HT-29 and A549 cell lines in vitro.		PAFR
TN4626	Nardosinonediol		Others
	Nardosinonediol shows cytotoxic activity against P-388 cells.		Others
TN2695	2,3-Dihydroamentoflavone 7,4'-dimethyl ether		Others
	2,3-Dihydroamentoflavone 7,4'-dimethyl ether exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 and/or HT-29 cell lines in vitro.		Others
T75664	(R)-Eucomol
	(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].
T25000	Acetylaleuritolic acid	NSC 266221,NSC-266221,NSC266221
	Acetylaleuritolic acid is a pentacyclic triterpenoid, plant metabolite isolated from the leaves of Garcinia miniata. It has antitumor properties, showing tumor inhibitory activity in tests against P-388 lymphoblastic leu...
T32372	Keenamide A
	Keenamide A, a cytotoxic cyclic hexapeptide, exhibits significant activity towards the P-388, A-549, MEL-20, and HT-29 tumor cell lines, but was inactive against the D6 and W2 Plasmodium falciparum malarial clones.
TN3704	Coronalolide		HIV Protease
	Coronalolide shows significant cytotoxic activities in P-388 cell line, it also displays significant anti-HIV activities in the HIV-1RT assay. Coronalolide and coronalolide methyl ester show broad cytotoxic activity agai...		HIV Protease
TN3292	8-Prenyldaidzein		Others
	8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging.		Others
TN1993	Norsanguinarine		Antifection
	Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic activities (ED (50) values < 4 microg/ml) against P-388, KB16, ...		Antifection
T79984	Chaparrinone		Parasite
	Chaparrinone, a quassinoid derived from the root of Eurycoma harmandiana, exhibits antimalarial and cytotoxic properties, with IC50 values of 0.037 μg/mL against Plasmodium falciparum and 0.34 μg/mL against P-388 cells [...		Parasite
TN2311	Wulignan A1		Antifection
	Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities.		Antifection
TN5133	3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone		HIV Protease , Topoisomerase
	5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptas...		HIV Protease , Topoisomerase