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Search Results for " nep "

20

Compounds

Cat No. Product Name Synonyms Targets
T40044 NEP VDP-green (NEP)
NEP, a turn-on fluorescent probe employing the intramolecular charge transfer (ICT) mechanism, facilitates the detection of vicinal dithiol-containing proteins (VDPs). Notably, NEP exhibits exceptional selectivity toward...
T10918 NEP-IN-1 Neprilysin
NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders.
T71118 NEP-28
NEP-28 is an AR agonist. NEP28 is a new SARM exhibiting high selectivity for androgen receptor. NEP28 showed tissue-selective effect equivalent to or higher than existing SARMs. In addition, the administration of NEP28 i...
TP1989 NEP(1-40) Nogo-66 (1-40)
Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS ...
T15696 NEP-IN-2 Others
NEP-IN-2 is an inhibitor of neutral endopeptidase. It also is used in the research of proliferation in atherosclerosis, restenosis.
T81685 NEP(1-40) TFA
NEP(1-40) TFA is a peptide antagonist of the Nogo-66 receptor (NgR), which mitigates the shift in microglial morphology distributions due to injury by attenuating myelin-derived inhibition [1].
T7693 Thiorphan Neprilysin
Thiorphan is an neprilysin inhibitor (NEP; IC50 : 0.007 μM).
T1176 Racecadotril Acetorphan Neprilysin , Proteasome
Racecadotril (Acetorphan) has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
TQ0106 Sacubitrilat LBQ-657 Neprilysin
Sacubitrilat (LBQ-657) (LBQ657) is an effective inhibitor of active neprilysin (NEP).
T4574 Sacubitril AHU 377,AHU377,AHU-377 Neprilysin
Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696.
T71116 MPT0B098
MPT0B098 is a potent microtubule inhibitor through binding to the colchicine-binding site of tubulin. MPT0B098 is active against the growth of various human cancer cells, including chemoresistant cells with IC50 values r...
T4200 Sacubitril hemicalcium salt AHU-377 (hemicalcium salt),AHU377 calcium salt Neprilysin
Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ...
T2318 Sacubitril/Valsartan Sacubitril mixture with Valsartan,Valsartan,Sacubitril,LCZ696 Apoptosis , RAAS , Neprilysin
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.
T6627 Phosphoramidon Disodium Phosphoramidon Disodium Salt RAAS , Neprilysin , Others
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.
T8140 Tianeptine S-1574,JNJ-39823277,Tianeptine sodium,TPI-1062 5-HT Receptor
Tianeptine (Tianeptine sodium) is a selective 5-HT uptake facilitator in vitro and in vivo.
T15259 Evatanepag CP-533536 free acid Prostaglandin Receptor
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...
T18924 Benzenepentacarboxylic Acid Pentacarboxybenzene Others
Benzenepentacarboxylic Acid (Pentacarboxybenzene) is a novel fluorescent probe to detect and scavenge HO-. Benzenepentacarboxylic acid is utilized to prove and detect the generation of HO- in H2O2/TAED and H2O2/TBCC alka...
T23380 Sonepiprazole Dopamine Receptor
Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4...
T0537 Desbenzyl Donepezil Hydrochloride Others
Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil.
T0368 Cinepazide maleate MD-67350,Vasodistal,Brendil Calcium Channel
Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator.
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