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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40044 | NEP | VDP-green (NEP) | |
NEP, a turn-on fluorescent probe employing the intramolecular charge transfer (ICT) mechanism, facilitates the detection of vicinal dithiol-containing proteins (VDPs). Notably, NEP exhibits exceptional selectivity toward... | |||
T10918 | NEP-IN-1 | Neprilysin | |
NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders. | |||
T71118 | NEP-28 | ||
NEP-28 is an AR agonist. NEP28 is a new SARM exhibiting high selectivity for androgen receptor. NEP28 showed tissue-selective effect equivalent to or higher than existing SARMs. In addition, the administration of NEP28 i... | |||
TP1989 | NEP(1-40) | Nogo-66 (1-40) | |
Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS ... | |||
T15696 | NEP-IN-2 | Others | |
NEP-IN-2 is an inhibitor of neutral endopeptidase. It also is used in the research of proliferation in atherosclerosis, restenosis. | |||
T81685 | NEP(1-40) TFA | ||
NEP(1-40) TFA is a peptide antagonist of the Nogo-66 receptor (NgR), which mitigates the shift in microglial morphology distributions due to injury by attenuating myelin-derived inhibition [1]. | |||
T7693 | Thiorphan | Neprilysin | |
Thiorphan is an neprilysin inhibitor (NEP; IC50 : 0.007 μM). | |||
T1176 | Racecadotril | Acetorphan | Neprilysin , Proteasome |
Racecadotril (Acetorphan) has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis. | |||
TQ0106 | Sacubitrilat | LBQ-657 | Neprilysin |
Sacubitrilat (LBQ-657) (LBQ657) is an effective inhibitor of active neprilysin (NEP). | |||
T4574 | Sacubitril | AHU 377,AHU377,AHU-377 | Neprilysin |
Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. | |||
T71116 | MPT0B098 | ||
MPT0B098 is a potent microtubule inhibitor through binding to the colchicine-binding site of tubulin. MPT0B098 is active against the growth of various human cancer cells, including chemoresistant cells with IC50 values r... | |||
T4200 | Sacubitril hemicalcium salt | AHU-377 (hemicalcium salt),AHU377 calcium salt | Neprilysin |
Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ... | |||
T2318 | Sacubitril/Valsartan | Sacubitril mixture with Valsartan,Valsartan,Sacubitril,LCZ696 | Apoptosis , RAAS , Neprilysin |
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure. | |||
T6627 | Phosphoramidon Disodium | Phosphoramidon Disodium Salt | RAAS , Neprilysin , Others |
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. | |||
T8140 | Tianeptine | S-1574,JNJ-39823277,Tianeptine sodium,TPI-1062 | 5-HT Receptor |
Tianeptine (Tianeptine sodium) is a selective 5-HT uptake facilitator in vitro and in vivo. | |||
T15259 | Evatanepag | CP-533536 free acid | Prostaglandin Receptor |
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l... | |||
T18924 | Benzenepentacarboxylic Acid | Pentacarboxybenzene | Others |
Benzenepentacarboxylic Acid (Pentacarboxybenzene) is a novel fluorescent probe to detect and scavenge HO-. Benzenepentacarboxylic acid is utilized to prove and detect the generation of HO- in H2O2/TAED and H2O2/TBCC alka... | |||
T23380 | Sonepiprazole | Dopamine Receptor | |
Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4... | |||
T0537 | Desbenzyl Donepezil Hydrochloride | Others | |
Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil. | |||
T0368 | Cinepazide maleate | MD-67350,Vasodistal,Brendil | Calcium Channel |
Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator. |