nas — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7856	Naphthol AS-E	nAS-E	Epigenetic Reader Domain , Histone Acetyltransferase
	Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.		Epigenetic Reader Domain , Histone Acetyltransferase
T69959	NAS-181 free base
	NAS-181 free base is a 5-HT(1B) receptor antagonist.
T62585	NAS-181
	NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.
T23055	NAS181	NAS-181	Others
	rat 5-HT1B receptor antagonist		Others
T0889	Saccharin	O-Sulfobenzimide,O-Benzoic sulfimide,Saccharimide,Benzoic sulfimide	Others , Antibacterial
	Saccharin (O-Sulfobenzimide) is a flavoring agent and non-nutritive sweetener.		Others , Antibacterial
T69958	Tofacitinib maleate
	Tofacitinib maleate, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib maleate modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STA...
T19529	Proteinase		Others
	Proteinases are enzymes that catalyse the breakdown of proteins. Proteinases are involved in many biological functions, including the digestion of ingested proteins, the breakdown of old proteins, and cell signalling. Th...		Others
T11580	Heme Oxygenase-1-IN-1	HO-1-IN-1	Reactive Oxygen Species
	Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).		Reactive Oxygen Species
TN6931	Anemarrhenasaponin Ia	(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxan	Others
	Anemarrhenasaponin Ia ((2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]...		Others
TP1216	CaM kinase II inhibitor TFA salt	Autocamtide-2-related inhibitory peptide (TFA)	CaMK
	CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.		CaMK
T4191	Multi-kinase inhibitor 1	Multi-kinase inhibitor I	Others , Bcr-Abl , PDGFR , c-Kit
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.		Others , Bcr-Abl , PDGFR , c-Kit
T21205	Ponasterone A	AI3-44686	Others
	Ponasterone A (AI3-44686) is an analog of 20-hydroxy ecdysone. Ecdysone has been used to induce mammalian expression systems.		Others
TQ0062	Nastorazepide	Z-360	cholecystokinin
	Nastorazepide (Z-360) is a selective, orally available antagonist of gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.		cholecystokinin
T60108	PDGFR Tyrosine Kinase Inhibitor III	PDGF Receptor Tyrosine Kinase Inhibitor III	PDGFR
	PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF...		PDGFR
T77648	Casein kinase 1δ-IN-14	WAY-637081	Others
	Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.		Others
T37385	Glutaminase-IN-3		Glutaminase
	Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.		Glutaminase
TP1115	L-Asparaginase	L-ASNase	Others
	L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a...		Others
T9040	Aurora kinase inhibitor-2	IUN-70219,Aurora Kinase Inhibitor II	Aurora Kinase
	Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).		Aurora Kinase
T11184	EML4-ALK kinase inhibitor 1	EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1	ALK
	EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.		ALK
T8591	RNase L-IN-2	5-(3-hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one	Others
	RNase L-IN-2 is an activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic a...		Others