Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 33.00 | |
100 mg | In stock | $ 47.00 | |
200 mg | In stock | $ 68.00 | |
500 mg | In stock | $ 112.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 52.00 |
Description | Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor. |
Targets&IC50 | KIX-KID:2.26 μM (IC50) |
In vivo | nAS-E could reverse bone loss induced by MDA-MB-231 tumour.?These results suggest that small molecules targeting CREB-CBP interaction to inhibit CREB-mediated gene transcription might be a potential approach for the treatment of breast cancer bone metastasis[1]. |
Synonyms | nAS-E |
Molecular Weight | 297.74 |
Formula | C17H12ClNO2 |
CAS No. | 92-78-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.98 mg/mL (10 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Naphthol AS-E 92-78-4 Chromatin/Epigenetic Histone Acetyltransferase Epigenetic Reader Domain Naphthol AS E inhibit CBP KIX-KID A549 Inhibitor nAS-E MCF-7 HAT Naphthol ASE CREB cancer HATs inhibitor