l-dopa — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0848	L-DOPA	Levodopa,3,4-Dihydroxyphenylalanine	Dopamine Receptor , Endogenous Metabolite
	L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...		Dopamine Receptor , Endogenous Metabolite
T31570	DPBX-L-Dopa	DPBX L-Dopa
	DPBX-L-Dopa is a boron-containing dopa-derivative, acting as a bladder relaxant through non-catecholamine receptors.
T36122	3-O-methyl-L-DOPA (hydrate)
	3-O-methyl-L-DOPA is a metabolite of L-DOPA , produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.
T24047	Etilevodopa hydrochloride	Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester	Others , Dopamine Receptor , Drug Metabolite
	Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.		Others , Dopamine Receptor , Drug Metabolite
T26288	Clovamide	trans-Clovamide,N-trans-Caffeoy-L-dopa	Apoptosis , Influenza Virus , ROS , Antibacterial
	Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprot...		Apoptosis , Influenza Virus , ROS , Antibacterial
T74180	[18F]-Labeled L-dopa precursor
	[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa[1].
T31823	Fluorodopa F 18	Fluorodopa (18F),6-(18F)Fluoro-L-DOPA,F-DOPA,L-6-(18F)Fluoro-DOPA,6-(18F)Fluorodopamine
	Fluorodopa F 18 can be used as radioactive agent.
T34589	SD-1077	d3-L-DOPA,deuldopa,deuterated levodopa,SD1077
	SD-1077, also known as d3-L-DOPA, is a deuterium containing levodopa. SD-1077 has been shown in preclinical models to improve the half-life of dopamine in the brain resulting in a prolonged treatment effect.
T15255	Etilevodopa	Levodopa ethyl ester,L-DOPA ethyl ester	Others
	Etilevodopa is an ethyl-ester prodrug of Levodopa which is used for the treatment of Parkinson's disease (PD). It is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Levo...		Others
T1517	Benserazide hydrochloride	Benserazide HCl,Serazide,Ro 4-4602	Dopamine Receptor
	Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.		Dopamine Receptor
T7746	Eltoprazine dihydrochloride		Others
	Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD pati...		Others
TP2050L	CTAP(TFA） (103429-32-9 free base)	CTAP(TFA）	Opioid Receptor
	CTAP(TFA) (103429-32-9 free base) is a potent, highly selective, and brain-penetrant antagonist of the μ-opioid receptor with IC50 of 3.5 nM. It displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somato...		Opioid Receptor
T3737	3-(2,4-Dihydroxyphenyl)propanoic acid	Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid	Tyrosinase
	3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid. It is generated by abkar1...		Tyrosinase
T4S1962	Beta-Asarone	Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin	NF-κB , JNK
	1. beta-Asarone (Cis-Isoelemicin) may be a potential preventive drug for Alzheimer's disease. 2. Beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. 3. The co-administration of be...		NF-κB , JNK
T8637	DMNB	6-Nitroveratraldehyde	DNA-PK
	DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human c...		DNA-PK
T0115	Idazoxan hydrochloride	RX 781094	Adrenergic Receptor , Imidazoline Receptor
	Idazoxan hydrochloride (RX 781094) is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity.		Adrenergic Receptor , Imidazoline Receptor
T15701	Methyldopa hydrochloride	L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride	Others
	L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme...		Others
TN1314	6-Hydroxykaempferol		Tyrosinase
	6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.		Tyrosinase
T16279	Nebicapone	BIA 3-202	Others
	Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor and is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to ...		Others
TMA2419	Catalponol		cAMP
	Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the increased levels of cyclic AMP.		cAMP