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Search Result

Search Results for " jp "

25

Compounds

1

Natural Products

4

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T25560 JP-8g JP 8g,JP8g
JP-8g has an anti-cancer and anti-inflammatory that acts through nitric oxide synthase signaling pathways.
T24064 Fipamezole JP-1730,BVF-025,JP 1730,JP1730 Adrenergic Receptor
Fipamezole is a potent alpha2 adrenergic receptor antagonist that may be useful for studying autonomic dysfunction in Parkinson's disease.
T22882 JP1302 Adrenergic Receptor
JP1302 is a selective α2C adrenoceptor antagonist with a Kb value of 16 nM and a Ki of 28 nM for human α2C receptors.JP1302 has antidepressant activity, disrupts the FACT complex and degrades histone H1.JP1302 has been u...
T11726 JP1302 dihydrochloride Adrenergic Receptor
JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Ki (binding affinity) value of 28 nM and a Kb value (antagonist activity) of 16 nM.
T32313 JP7 JP-7,JP 7
JP7 is a hemoglobin allosteric modifier.
T27321 Fipamezole HCl MPV1730,JP1730,MPV-1730,MPV 1730,JP 1730,JP-1730
Fipamezole HCl, a α2-adrenoceptor antagonist, is used potentially for the treatment of dyskinesia associated with Parkinson's disease.
TQ0081 JPH203 KYT-0353 Others
JPH203 (KYT-0353) is a potent and specific inhibitor of L-type amino acid transporter protein 1 (LAT-1). JPH203 inhibits cellular uptake of leucine, inhibits cell proliferation, induces apoptosis, and possesses anti-infl...
T8857 LJP-1586 HCl LJP 1586,LJP-1586 hydrochloride,LJP-1586,LJP1586 Others
LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (IC...
T11727 JPH203 dihydrochloride KYT-0353 dihydrochloride Others
JPH203 dihydrochloride (KYT-0353 dihydrochloride) is a tyrosine analog, acts as a selective inhibitor of L-type amino acid transporter 1 (LAT1), and is used in cancer research.
T15626 JPM-OEt Others
JPM-OEt is a broad spectrum cysteine cathepsin inhibitor with antitumor activity. JPM-OEt binds covalently in the active site and irreversibly inhibits the cysteine cathepsin family.
T32315 JPB 25 BRN0977600,JPB25,BRN-0977600,JPB-25,BRN 0977600
JPB 25 is a bioactive chemical.
T74454 JPS016
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC). It serves as a potent HDAC1/2 degrader, resulting in a signific...
T74456 JPS036
JPS036, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), efficiently degrades class I histone deacetylase (HDAC), particularly HDAC1/2. Its activity results in a substantial inc...
T77938 JPS016 TFA HDAC
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a substa...
T79524 JPC0323 5-HT Receptor
JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate brain penetration. It is utilized in research pertaining to neu...
T77966 SJPYT-195
SJPYT-195 is a cytotoxic agent targeting GSPT1 for degradation, suitable for PROTAC (PROteolysis TArgeting Chimera) synthesis [1].
T71056 SJP-L-5
SJP-L-5 is a inhibitor of HIV-1 infection by blocking viral DNA nuclear entry.
T74149 JPD447
JPD447, a derivative of MAC-0547630, represents a new class of UppS inhibitors designed to enhance the efficacy of β-lactam antibiotics.
T74650 JPE-1375
JPE-1375, a complement C5a receptor 1 (C5aR1) antagonist, effectively inhibits polymorphonuclear leukocyte mobilization (EC50=6.9 µM) and reduces TNF levels (EC50=4.5 µM) in mice, making it useful for autoimmune and infl...
T74453 JPS014
JPS014, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), exhibiting potency as an HDAC1/2 degrader. This correlation is ...
T77937 JPS014 TFA HDAC
JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a hi...
T74455 JPS035
JPS035, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), specifically HDAC1/2. Its potent activity is associated with an...
T69955 JPI-547 HCl
JPI 547, also known as NOV 1402, is an oral inhibitor of PARP 1/2 and Tankyrase 1/2. JPI-547 demonstrated anti-tumor activity in BRCA-deficient xenograft models as a single-agent and in combination with chemotherapy and ...
T78593 JP104 FAAH
JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].
T27693 JPC-211 JPC 211,PNU-99194A free base
JPC-211 is an agonist of dopamine-receptor.
Cat No. Product Name Synonyms Targets
TN4015 JP-2 Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate Others
JP-2 is a natural product for research related to life sciences. The catalog number is TN4015 and the CAS number is 60263-06-1.

Natural Products

JP-2
TN4015
Synonym: Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate
Target: Others

Recombinant Proteins

Species：
Apis mellifera (2)
HIV (1)
Human (1)
Expression System：
E. coli (2)
HEK293 (1)
Yeast (1)
Tag：
His (1)
His,MBP (1)
N-terminal 6xHis-tagged (1)
N-terminal GST-tagged (1)
Cat No. Product Name Species Expression System
TMPY-00732 Cathepsin C Protein, Human, Recombinant (His) Human HEK293
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also kno...
TMPH-00065 MRJP1 Protein, Apis mellifera, Recombinant (GST) Apis mellifera E. coli
Induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vite...
TMPH-00064 MRJP1 Protein, Apis mellifera, Recombinant (His) Apis mellifera Yeast
Induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vite...
TMPY-04061 HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) HIV E. coli
HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) is expressed in E. coli with His and MBP tag. The predicted molecular weight is 58.8 kDa. Accession number: L8B302
Cat No. Product Name
L1010 FDA-Approved & Pharmacopeia Drug Library

3157 compounds
3157 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS);

Libraries

FDA-Approved & Pharmacopeia Drug Library
L1010
Compounds: 3157
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