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Search Results for " gpcr "

20

Compounds

Cat No. Product Name Synonyms Targets
T40685L Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (600171-70-8 Free base) Others
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (Orphan GPCR SP9155 agonist P550 ) is a member of the RFamide peptide family with orexigenic effects.
T60074 GPCR agonist-2 4-(Cyclopropylamino)-3-nitrobenzoic acid GPR
GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.
T40685 Orphan GPCR SP9155 agonist P550 (mouse, rat) 26RFa (mouse, rat),Orphan GPCR SP9155 agonist P550 (mouse, rat)
Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)) is an orphan GPCR with an orexigenic effect belonging to the RFamide peptide family. It acts as the cognate ligand for the mouse orphan receptor GPR103, w...
T9407 Rasarfin Others , Ras
Rasarfin inhibits Ras and ARF6.
T9357 Ro 5212773 Epptb Others
Ro 5212773 (Epptb) is a selective TAAR1 antagonist.
T21874 CID 2745687 GPR
CID 2745687 is a GPR35 antagonist that inhibited the effects at human GPR35 of cromolyn disodium and zaprinast, two agonists that share an overlapping binding site.
T8329 AR 231453 GPR
AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.
T15432 GSK256073 GPR , Others
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inh...
T0853 Adenosine D-Adenosine,Adenine riboside Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy
Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
T9146 Ms48107 Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro- Others
MS48107 is a potent, selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68), demonstrating specificity for GPR68 over closely related proton GPCRs, neurotransmitter transporters, and hERG ion ch...
T2613 Almorexant ACT 078573 OX Receptor
Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
T14063 7α,25-Dihydroxycholesterol 7α,25-OHC EBI2/GPR183 , Endogenous Metabolite
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cel...
T6155 Almorexant hydrochloride ACT-078573 hydrochloride,Almorexant HCl OX Receptor
Almorexant hydrochloride (ACT-078573 hydrochloride) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
T12684 Radioprotectin-1 5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid LPA Receptor
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
T10363 Arazine N-Acetyl-S-farnesyl-L-cysteine Others
Arazine (N-Acetyl-S-farnesyl-L-cysteine) can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Arazine is a cell-permeable modulator of G protein and G...
T3433 TUG-891 TUG 891,TUG891 GPR
TUG-891 is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids.
T9162 CID1231538 GPR
CID1231538 is a potent GPR35 antagonist.
TQ0194 Trans-Vaccenic acid TVA,(11E)-octadec-11-enoic acid,11E)-octadec-11-enoic acid Endogenous Metabolite
Trans-Vaccenic acid (TVA) is a naturally occurring trans-fatty acid found in ruminant fats and dairy products that has antitumor activity by regulating CD8+ T cell proliferation through the GPCR-CREB pathway.Trans-Vaccen...
T3119 JNJ-63533054 JNJ 63533054 GPR
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
T50088 N-phenylthiophene-2-carboximidamide Others
N-phenylthiophene-2-carboximidamide is a thiophene derivative that functions as an inhibitor of protein tyrosine kinases (PTKs) and a ligand for G protein-coupled receptors (GPCRs).

Compounds

Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
T40685L
Synonym: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (600171-70-8 Free base)
Target: Others
GPCR agonist-2
T60074
Synonym: 4-(Cyclopropylamino)-3-nitrobenzoic acid
Target: GPR
Orphan GPCR SP9155 agonist P550 (mouse, rat)
T40685
Synonym: 26RFa (mouse, rat),Orphan GPCR SP9155 agonist P550 (mouse, rat)
Target:
Rasarfin
T9407
Synonym:
Target: Others, Ras
Ro 5212773
T9357
Synonym: Epptb
Target: Others
CID 2745687
T21874
Synonym:
Target: GPR
AR 231453
T8329
Synonym:
Target: GPR
GSK256073
T15432
Synonym:
Target: GPR, Others
Adenosine
T0853
Synonym: D-Adenosine,Adenine riboside
Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy
ms48107
T9146
Synonym: Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro-
Target: Others
Almorexant
T2613
Synonym: ACT 078573
Target: OX Receptor
7α,25-Dihydroxycholesterol
T14063
Synonym: 7α,25-OHC
Target: EBI2/GPR183, Endogenous Metabolite
Almorexant hydrochloride
T6155
Synonym: ACT-078573 hydrochloride,Almorexant HCl
Target: OX Receptor
Radioprotectin-1
T12684
Synonym: 5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid
Target: LPA Receptor
Arazine
T10363
Synonym: N-Acetyl-S-farnesyl-L-cysteine
Target: Others
TUG-891
T3433
Synonym: TUG 891,TUG891
Target: GPR
CID1231538
T9162
Synonym:
Target: GPR
trans-Vaccenic acid
TQ0194
Synonym: TVA,(11E)-octadec-11-enoic acid,11E)-octadec-11-enoic acid
Target: Endogenous Metabolite
JNJ-63533054
T3119
Synonym: JNJ 63533054
Target: GPR
N-phenylthiophene-2-carboximidamide
T50088
Synonym:
Target: Others
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TargetMol