Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 199.00 | |
2 mg | In stock | $ 299.00 | |
5 mg | In stock | $ 399.00 | |
10 mg | In stock | $ 677.00 | |
25 mg | In stock | $ 1,177.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 451.00 |
Description | Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action. |
Targets&IC50 | murine LPA2 subtype:(EC50)25 nM |
In vitro | In MEF and IEC-6 cells expressing LPA2, Radioprotectin-1 (0, 0.1, 0.3, 1.0, and 3 μM) effectively reduces apoptosis induced by gamma-irradiation and the radiomimetic chemotherapeutic Adriamycin[1]. |
In vivo | In C57BL/6 female mice, Radioprotectin-1 (0.1 and 0.3 mg/kg; s.c.) decreases the mortality in models of the hematopoietic and gastrointestinal acute radiation syndrome[1]. |
Molecular Weight | 486.93 |
Formula | C23H19ClN2O6S |
CAS No. | 1622006-09-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 100 mg/mL (205.4 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Radioprotectin-1 1622006-09-0 GPCR/G Protein LPA Receptor Inhibitor inhibitor inhibit