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20

Compounds

Cat No. Product Name Synonyms Targets
T8328 STING agonist-1 G10 Virus Protease , STING
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
T17402 Amino-PEG10-acid Others , PROTAC Linker
Amino-PEG10-acid is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T18031 Hydroxy-PEG10-acid HO-PEG10-CH2CH2COOH Others , PROTAC Linker
Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1].
T2038 RG108 N-Phthalyl-L-tryptophan DNA Methyltransferase
RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).
T67839 HG106 Others
HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene., which is anti-inflammatory and may be used to treat the growth of diseases...
T2693 AG1024 Tyrphostin AG 1024,Tyrphostin,AGS 200 Apoptosis , IGF-1R
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).
T2672 TG100-115 PI3K
TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.
T17964 Fmoc-NH-PEG10-acid Others , PROTAC Linker
Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker. Fmoc-NH-PEG10-acid can be used in the synthesis of PROTACs.
T14413 Azido-PEG10-alcohol Others , PROTAC Linker
Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
T3065 TG101209 Apoptosis , FLT , c-RET , JAK , Autophagy
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.
T39970 TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high efficacy against tumors. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonis...
T14223 Amino-PEG10-amine Others
Amino-PEG10-amine is a PEG-based PROTAC linker employed for the conjugation of two mono diethylstilbestrol (DES)-based ligands. This compound offers an alternative approach to the synthesis of highly selective and active...
T17612 Bis-PEG10-NHS ester Others
Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
T75848 PG106 TFA
PG106 TFA is a potent, selective antagonist of the human melanocortin 3 (hMC3) receptor, displaying an IC50 value of 210 nM, while exhibiting negligible activity at the hMC4 receptors (EC50 = 9900 nM) and hMC5 receptor [...
T78034 ANG1005
ANG1005 is a brain-penetrating peptide-agent conjugate comprising a taxane derivative that features three paclitaxel molecules covalently bonded to Angiopep-2. This design facilitates crossing of the blood-brain and bloo...
T40532 MS-PEG10-THP MS-PEG10-THP
MS-PEG10-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with...
T40531 THP-PEG10-OH THP-PEG10-OH
THP-PEG10-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with...
T18234 Mal-amido-PEG10-acid Others
Mal-amido-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T14414 Azido-PEG10-amine Others
Azido-PEG10-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...
T14412 Azido-PEG10-acid Others
Azido-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system ...
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TargetMol