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20

Compounds

Cat No. Product Name Synonyms Targets
T8834 EST64454 hydrochloride EST64454 Sigma receptor
EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.
T39284 EST73502 HCl Opioid Receptor
EST73502 is an agonist of μ-opioid receptor(Ki = 64 nM) agonist and an antagonist of σ1 receptor (Ki = 118 nM). EST73502 displays antinociceptive activity.
T9306 EST64454 Maleic acid salt Others
EST64454 Maleic acid salt is the maleic acid salt form of EST64454.EST64454 is a highly soluble σ1 receptor antagonist clinical candidate for the treatment of pain.
T70906 EHT-6706
EHT-6706 is a novel microtubule-disrupting agent that targets the colchicine-binding site to inhibit tubulin polymerization. At low nM concentrations, EHT 6706 exhibits highly potent antiproliferative activity on more th...
T13166 TK216 Others , DNA/RNA Synthesis
TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.
T9669 EST73502 hydrochloride
EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with K i s of 64 nM and 118 nM for MOR and σ1R, respecti...
T70908 EST64454 free base
EST64454 is a σ1 receptor (σ1R) antagonist clinical candidate for the treatment of pain. EST64454 shows an outstanding aqueous solubility, which together with its high permeability in Caco-2 cells will allow its classifi...
T38888 Azide-PEG3-Desthiobiotin Azide-PEG3-Desthiobiotin
Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
T18560 Propargyl-C1-NHS ester 4-Pentynoic Acid Succinimidyl Ester Others
Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) is a nonclaevable linker used for antibody-drug-conjugation (ADC).
T12832 Amcenestrant SAR439859 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Amcenestrant (SAR439859) is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC50 of 0.2 nM for ERα degradation).
T5240 Cholestenone (+)-4-Cholesten-3-one Others , Endogenous Metabolite
Cholestenone ((+)-4-Cholesten-3-one) is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals.
T17842 DOTA-​NHS-​ester Others
DOTA-NHS-ester is a linker of affibody molecules for small animal PET, SPECT and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for tumor detection.
T18987 Py-BODIPY-NHS ester Autophagy
Py-BODIPY-NHS ester is a small molecular dye with strong UV absorption that can be used to label living cells and immobilise cells.
T14594 Biotin-PEG3-NHS ester Others
Biotin-PEG3-NHS ester is a PROTAC linker based on the PEG structure and can be used to prepare PROTAC.
T18476 N3-Ph-NHS ester Others
N3-Ph-NHS ester is a noncleavable ADC linker. N3-Ph-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs).
T17655 Boc-NH-O-C1-NHS ester Others , PROTAC Linker
Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis.
T35317 Zopolrestat CP 73850,CP73850,CP-73850,Zopolrestatum Reductase
Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).
T18466 N3-C3-NHS ester Others
N3-C3-NHS ester is a noncleavable ADC linker. N3-C3-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs).
T8043 5α-Cholestane Endogenous Metabolite
5α-Cholestane belongs to the cholestane steroid class of compounds.
T15976 Mal-PEG1-NHS ester Others , PROTAC Linker
Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It also is PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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