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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8834 | EST64454 hydrochloride | EST64454 | Sigma receptor |
EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management. | |||
T39284 | EST73502 HCl | Opioid Receptor | |
EST73502 is an agonist of μ-opioid receptor(Ki = 64 nM) agonist and an antagonist of σ1 receptor (Ki = 118 nM). EST73502 displays antinociceptive activity. | |||
T9306 | EST64454 Maleic acid salt | Others | |
EST64454 Maleic acid salt is the maleic acid salt form of EST64454.EST64454 is a highly soluble σ1 receptor antagonist clinical candidate for the treatment of pain. | |||
T70906 | EHT-6706 | ||
EHT-6706 is a novel microtubule-disrupting agent that targets the colchicine-binding site to inhibit tubulin polymerization. At low nM concentrations, EHT 6706 exhibits highly potent antiproliferative activity on more th... | |||
T13166 | TK216 | Others , DNA/RNA Synthesis | |
TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity. | |||
T9669 | EST73502 hydrochloride | ||
EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with K i s of 64 nM and 118 nM for MOR and σ1R, respecti... | |||
T70908 | EST64454 free base | ||
EST64454 is a σ1 receptor (σ1R) antagonist clinical candidate for the treatment of pain. EST64454 shows an outstanding aqueous solubility, which together with its high permeability in Caco-2 cells will allow its classifi... | |||
T38888 | Azide-PEG3-Desthiobiotin | Azide-PEG3-Desthiobiotin | |
Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules. | |||
T18560 | Propargyl-C1-NHS ester | 4-Pentynoic Acid Succinimidyl Ester | Others |
Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) is a nonclaevable linker used for antibody-drug-conjugation (ADC). | |||
T12832 | Amcenestrant | SAR439859 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Amcenestrant (SAR439859) is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC50 of 0.2 nM for ERα degradation). | |||
T5240 | Cholestenone | (+)-4-Cholesten-3-one | Others , Endogenous Metabolite |
Cholestenone ((+)-4-Cholesten-3-one) is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals. | |||
T17842 | DOTA-NHS-ester | Others | |
DOTA-NHS-ester is a linker of affibody molecules for small animal PET, SPECT and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for tumor detection. | |||
T18987 | Py-BODIPY-NHS ester | Autophagy | |
Py-BODIPY-NHS ester is a small molecular dye with strong UV absorption that can be used to label living cells and immobilise cells. | |||
T14594 | Biotin-PEG3-NHS ester | Others | |
Biotin-PEG3-NHS ester is a PROTAC linker based on the PEG structure and can be used to prepare PROTAC. | |||
T18476 | N3-Ph-NHS ester | Others | |
N3-Ph-NHS ester is a noncleavable ADC linker. N3-Ph-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T17655 | Boc-NH-O-C1-NHS ester | Others , PROTAC Linker | |
Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis. | |||
T35317 | Zopolrestat | CP 73850,CP73850,CP-73850,Zopolrestatum | Reductase |
Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM). | |||
T18466 | N3-C3-NHS ester | Others | |
N3-C3-NHS ester is a noncleavable ADC linker. N3-C3-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T8043 | 5α-Cholestane | Endogenous Metabolite | |
5α-Cholestane belongs to the cholestane steroid class of compounds. | |||
T15976 | Mal-PEG1-NHS ester | Others , PROTAC Linker | |
Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It also is PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |