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Search Results for " e7 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1554L	HPV16 E7 (86-93) acetate	HPV16 E7 (86-93) acetate(160212-93-1 Free base)	Others
	HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.		Others
T38919	Protein E7(43-62)	Protein E7(43-62)
	Protein E7(43-62) is a peptide derived from the E7 protein. The peptide spans the 43rd to 62nd amino acid residues and exhibits anti-tumor effects.
TP1525	HPV16 E7 (86-93) (TFA)(160212-93-1,free)	HPV16 E7 (86-93) (TFA)
	HPV16 E7 (86-93) TFA is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide.
TP1595	Human Papillomavirus (HPV) E7 protein (49-57)	Human Papillomavirus (HPV) E7 protein 49-57
	Human Papillomavirus (HPV) E7 protein (49-57) is the H-2d-restricted human papillomavirus (HPV) E749-57 epitope.
TP1554	HPV16 E7 (86-93)
	This is amino acids 86 to 93 fragment of the human papilloma virus (HPV) type 16 oncoprotein E7. This HPV16-encoded peptide has very high affinity of binding to the HLA-A*0201 molecule.This immunogenic fragment may be us...
T81369	Protein E7(43-62) TFA
	Protein E7(43-62) TFA, a short peptide derived from the E7 protein spanning amino acid residues 43 to 62, exhibits anti-tumor properties [1].
T76015	HPV16 E7 (86-93) (TFA)
	HPV16 E7 (86-93) TFA, a peptide derived from HPV16 E7, is restricted by human leukocyte antigen (HLA)-A2.1 and exhibits immunogenic properties in cervical carcinomas [1] [2].
T8350	TPCK		Proteasome
	TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis		Proteasome
T4471	E7449	Stenoparib,UNII-9X5A2QIA7C	Others , PARP
	E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ～50 and ～50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.		Others , PARP
T4435	E7820	ER68203-00	Integrin
	E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).		Integrin
T2116	AEE788	NVP-AEE 788	Apoptosis , EGFR , c-Fms , FLT , Bcr-Abl
	AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.		Apoptosis , EGFR , c-Fms , FLT , Bcr-Abl
T61189	E7016	GPI 21016	PARP
	E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.		PARP
TQ0025	E7046		Prostaglandin Receptor
	E7046 is a specific, orally bioavailable EP4 antagonist (IC50: 13.5 nM, Ki: 23.14 nM), exhibiting anti-tumor activities.		Prostaglandin Receptor
TP1515	HPV16-E711-20 epitope
	HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro.
T24023	E7107	E-7107,E 7107
	E7107 is a first-in-class inhibitor of precursor messenger ribonucleic acid spliceosome.
T78559	PDE7-IN-3
	PDE7-IN-3 (Example 2) serves as an inhibitor of phosphodiesterase PDE7 and exhibits potential analgesic properties. It is applicable in the research of various pain types including inflammatory, neuropathic, visceral, an...
T83702	E70K TFA
	E70K is a compound that inhibits the interaction between the chemokine (C-X-C) ligand 8 (CXCL8) and glycosaminoglycans (GAGs) on cell membrane surfaces. It mimics a segment of the CXCL8 protein's GAG-binding region at th...
T76446	(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P
	(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P is a selective NK 1 receptor antagonist [1] .
T76303	(p-Iodo-Phe7)-ACTH (4-10)
	(p-Iodo-Phe7)-ACTH (4-10), a derivative of adrenocorticotrophic hormone (ACTH) produced by the anterior pituitary gland, functions as a melanocortin (MC) receptor antagonist. It effectively inhibits α-melanocyte-stimulat...
T72749	E7090 succinate
	E7090 succinate is a selective, potent, orally-administered inhibitor of FGFR1, FGFR2, and FGFR3 tyrosine kinase activities, demonstrating IC50 values of 0.71 nM (FGFR1), 0.50 nM (FGFR2), 1.2 nM (FGFR3), and 120 nM (FGFR...
T32240	IVDE77	IVDE-77,IVDE 77
	IVDE77 is the first Ang IV-analogue with the ability to abolish IRAP-availability completely at the cell surface in vitro.
T83497	[D-Pro2,D-Phe7,D-Trp9] Substance P
	[D-Pro2,D-Phe7,D-Trp9] Substance P, an analogue of Substance P, serves as an inhibitor to its parent compound and indirectly contracts the guinea-pig ileum (GPI) [1] [2].
T76347	Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
	Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect in rat models [1] [2].
T80525	E70K		CXCR
	E70K, a CXCL8 C-terminal peptide, features a lysine (K) substitution for glutamic acid (E) at position 70 and has demonstrated the ability to attenuate neutrophil adhesion and migration in the context of inflammation [1]...		CXCR
T69003	E7974
	E7974 is an analog of the sponge-derived anti-microtubule tripeptide hemiasterlin with antimitotic and potential antineoplastic activities. Hemiasterlin analog E7974 binds to the Vinca domain on tubulin, resulting in inh...
T9563	Type III-Intermediate7
	Type III-Intermediate7 is a useful organic compound for research related to life sciences and the catalog number is T9563.
T70441	1E7-03
	1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).
T72392	E7766 diammonium salt
	E7766 diammonium salt, a macrocycle-bridged STING agonist, exhibits a dissociation constant (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor activities.
T24606	PDE7 inhibitor S14	PDE7 inhibitor-S14,S14
	PDE7 inhibitor S14 is a cell-permeable PDE7 inhibitor that acts by targeting the cyclic adenosine monophosphate (cAMP)/cAMP-response element-binding protein (CREB) pathway.
T76436	[MePhe7]-Neurokinin B
	[MePhe7]-Neurokinin B is a neurokinin NK-3 receptor (NK3R) agonist, exhibiting a potent agonistic activity with an IC50 value of 3 nM. It acts as a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) s...
T22491	PDE7-IN-2		PDE
	PDE7-IN-2 is an inhibitor of phosphodiesterase 7 (IC50 = 2.1 µM) and can be used in Parkinson's disease studies.		PDE
T76346	(D-Phe7)-α-MSH
	(D-Phe7)-α-MSH is an α-MSH analogue [1] .
T72811	E7766 disodium
	E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.
T27234	E7090	E-7090,E 7090
	E-7090 is a fibroblast growth factor receptor inhibitor. E-7090 is a selective inhibitor of the tyrosine kinase activities of FGFR1, -2, and -3.
T22320	E7766		Others
	E7766 is a novel macrocycle-bridged STING agonist (MBSA) with pan-genotypic and superior potency activity.		Others
T17228	Sabizabulin	ABI-231,VERU-111	Microtubule Associated
	Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin inhibits tumor growth and metastatic phenotypes of cervica...		Microtubule Associated
T13723	Homocarbonyltopsentin	PK4C9	Others
	Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM).		Others
T60544	HPV18-IN-1
	HPV18-IN-1 (Compound H1) is a potent HPV18 inhibitor that prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation with...
T76960	Verpasep caltespen
	Verpasep caltespen (HspE7), a recombinant fusion protein, originates from the Mycobacterium bovis Calmette-Guérin heat shock protein 65 (Hsp65) and is covalently bonded at its C-terminal end to the E7 protein of HPV16. T...

Compounds

HPV16 E7 (86-93) acetate

TP1554L

Synonym: HPV16 E7 (86-93) acetate(160212-93-1 Free base)

Target: Others

Protein E7(43-62)

T38919

Synonym: Protein E7(43-62)

Target:

HPV16 E7 (86-93) (TFA)(160212-93-1,free)

TP1525

Synonym: HPV16 E7 (86-93) (TFA)

Target:

Human Papillomavirus (HPV) E7 protein (49-57)

TP1595

Synonym: Human Papillomavirus (HPV) E7 protein 49-57

Protein E7(43-62) TFA

T81369

Synonym:

Target:

HPV16 E7 (86-93) (TFA)

Synonym: Stenoparib,UNII-9X5A2QIA7C

Target: Apoptosis, EGFR, c-Fms, FLT, Bcr-Abl

Target: Prostaglandin Receptor

HPV16-E711-20 epitope

Synonym: E-7107,E 7107

(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P

T76446

Synonym:

Target:

(p-Iodo-Phe7)-ACTH (4-10)

Synonym: IVDE-77,IVDE 77

Target:

[D-Pro2,D-Phe7,D-Trp9] Substance P

T83497

Synonym:

Target:

Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2

Type III-Intermediate7

E7766 diammonium salt

Synonym: PDE7 inhibitor-S14,S14

Target:

[MePhe7]-Neurokinin B

Synonym: E-7090,E 7090

Synonym: ABI-231,VERU-111

Target: Microtubule Associated

Homocarbonyltopsentin

Cat No.	Product Name	Synonyms	Targets
T79941	Antimycin A2c		Apoptosis
	Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer. It impedes HeLa cell proliferation by arresting the cell cycle at the S phase and induces cas...		Apoptosis

Natural Products

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-01506	HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD...
TMPK-01504	HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD...
TMPK-01505	HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD...
TMPH-01827	Human Papilloma Virus type 11 (HPV 11) Protein E7 (His & Myc)	HPV 11	E. coli
	Human Papilloma Virus type 11 (HPV 11) Protein E7 (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is P04020.
TMPH-01837	Human Papilloma Virus type 18 (HPV 18) Protein E7 (His)	HPV 18	P. pastoris (Yeast)
	Human Papilloma Virus type 18 (HPV 18) Protein E7 (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.0 kDa and the accession number is P06788.
TMPH-01834	Human Papilloma Virus type 16 (HPV 16) Protein E7 (His)	HPV 16	E. coli
	Human Papilloma Virus type 16 (HPV 16) Protein E7 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.0 kDa and the accession number is P03129.
TMPH-01838	Human Papilloma Virus type 52 (HPV 52) Protein E7 (His & SUMO)	HPV 52	E. coli
	Human Papilloma Virus type 52 (HPV 52) Protein E7 (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.0 kDa and the accession number is P36831.
TMPH-01836	Human Papilloma Virus type 18 (HPV 18) Protein E7 (E. coli, His)	HPV 18	E. coli
	Human Papilloma Virus type 18 (HPV 18) Protein E7 (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.0 kDa and the accession number is P06788.
TMPY-06107	SARS-CoV-2 Spike S2 Protein (E780Q, hFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S2 Protein (E780Q, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 84.7 kDa and the accession number is A0A6G7K2L4.
TMPH-01584	KRT7 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).