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20

Compounds

Cat No. Product Name Synonyms Targets
T9087 Creatine-d3 hydrate CREATINE-(METHYL-D3) MONOHYDRATE Endogenous Metabolite
Creatine-d3 hydrate (CREATINE-(METHYL-D3) MONOHYDRATE) is a deuterium labeled Creatine hydrate. Under physiological and in pathological conditions, Creatine hydrate is pivotal in energy metabolism of muscle and brain cel...
T5383 D3-βArr NCGC00379308 TSH Receptor
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
TN2089 Platycodin D3 HCV Protease , NF-κB
Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway mucin; it can significantly enhance mitogen- and OVA-induced...
TMA0835 Deapi-platycodin D3 Others
Deapi-platycodin D3 is a natural product isolate from the root of Platycodon grandiflorum.
T1135 Vitamin D3 Cholecalciferol,Colecalciferol Endogenous Metabolite
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
T28804 Slingshot inhibitor D3 JHN76359 Others
Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot.
T38553 Previtamin D3 Previtamin D3
Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).
T35501 5,6-trans-Vitamin D3 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A Vitamin
5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol) is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.
T12308 Omeprazole-d3 H 16868 D3 Others
Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)
T11853 Linezolid-d3 Linezolid D3,PNU-100766 D3 Others
Linezolid D3, a deuterium-labeled version of Linezolid, is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.
T6430 Calcifediol U 32070E,25-hydroxy Vitamin D3,RO 8-8892 Endogenous Metabolite
Calcifediol (U 32070E)(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
T12135 Mycophenolic acid-d3 Mycophenolate-d3,Mycophenolate D3 Others , Antibacterial
Mycophenolic acid-d3 (Mycophenolate-d3) is a derivative of Mycophenolic acid. Mycophenolic acid is a compound that reduces GTP level and impacts transcription elongation of RNA polymerase II (RNAP II), promotes proximal ...
T12487 Piroxicam D3 CP-16171 D3 Others
Piroxicam D3 is deuterium labeled Piroxicam. Piroxicam is a COX inhibitor(human monocyte COX-1 and COX-2 with IC50s of 47, 25 μM , respectively) .
T12046 Mirtazapine D3 Org3770 D3,6-Azamianserin D3 5-HT Receptor
Mirtazapine D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .
T11604 Ibuprofen-d3 Ibuprofen D3,(±)-Ibuprofen D3 Others
Ibuprofen D3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).
T16909 Donafenib Sorafenib (D3),Bay 43-9006 (D3),Sorafenib-d3 Raf , VEGFR
Donafenib (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
T12691 Rapamycin-d3 AY-22989-d3,Sirolimus-d3 Others
Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).
T12018 Methylnaltrexone-d3 bromide Methylnaltrexone D3 Bromide Others
Methylnaltrexone D3 Bromide is the deuterium labeled Methylnaltrexone Bromide.
T11692 Ivabradine-d3 hydrochloride Ivabradine D3 Hydrochloride Others
Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent. Ivabradine D3 Hydrochloride is the deuterium labeled Ivabradine hydrochloride.
T24725 ROCK-IN-D3 ROCK inhibitor D3,ROCK-inhibitor-D3
ROCK-IN-D3 is an effective and selective inhibitor of ROCK.

Compounds

Creatine-d3 hydrate
T9087
Synonym: CREATINE-(METHYL-D3) MONOHYDRATE
Target: Endogenous Metabolite
D3-βArr
T5383
Synonym: NCGC00379308
Target: TSH Receptor
Platycodin D3
TN2089
Synonym:
Target: HCV Protease, NF-κB
Deapi-platycodin D3
TMA0835
Synonym:
Target: Others
Vitamin D3
T1135
Synonym: Cholecalciferol,Colecalciferol
Target: Endogenous Metabolite
Slingshot inhibitor D3
T28804
Synonym: JHN76359
Target: Others
Previtamin D3
T38553
Synonym: Previtamin D3
Target:
5,6-trans-Vitamin D3
T35501
Synonym: 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A
Target: Vitamin
Omeprazole-d3
T12308
Synonym: H 16868 D3
Target: Others
Linezolid-d3
T11853
Synonym: Linezolid D3,PNU-100766 D3
Target: Others
Calcifediol
T6430
Synonym: U 32070E,25-hydroxy Vitamin D3,RO 8-8892
Target: Endogenous Metabolite
Mycophenolic acid-d3
T12135
Synonym: Mycophenolate-d3,Mycophenolate D3
Target: Others, Antibacterial
Piroxicam D3
T12487
Synonym: CP-16171 D3
Target: Others
Mirtazapine D3
T12046
Synonym: Org3770 D3,6-Azamianserin D3
Target: 5-HT Receptor
Ibuprofen-d3
T11604
Synonym: Ibuprofen D3,(±)-Ibuprofen D3
Target: Others
Donafenib
T16909
Synonym: Sorafenib (D3),Bay 43-9006 (D3),Sorafenib-d3
Target: Raf, VEGFR
Rapamycin-d3
T12691
Synonym: AY-22989-d3,Sirolimus-d3
Target: Others
Methylnaltrexone-d3 bromide
T12018
Synonym: Methylnaltrexone D3 Bromide
Target: Others
Ivabradine-d3 hydrochloride
T11692
Synonym: Ivabradine D3 Hydrochloride
Target: Others
ROCK-IN-D3
T24725
Synonym: ROCK inhibitor D3,ROCK-inhibitor-D3
Target:
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TargetMol