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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9087 | Creatine-d3 hydrate | CREATINE-(METHYL-D3) MONOHYDRATE | Endogenous Metabolite |
Creatine-d3 hydrate (CREATINE-(METHYL-D3) MONOHYDRATE) is a deuterium labeled Creatine hydrate. Under physiological and in pathological conditions, Creatine hydrate is pivotal in energy metabolism of muscle and brain cel... | |||
T5383 | D3-βArr | NCGC00379308 | TSH Receptor |
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation. | |||
TN2089 | Platycodin D3 | HCV Protease , NF-κB | |
Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway mucin; it can significantly enhance mitogen- and OVA-induced... | |||
TMA0835 | Deapi-platycodin D3 | Others | |
Deapi-platycodin D3 is a natural product isolate from the root of Platycodon grandiflorum. | |||
T1135 | Vitamin D3 | Cholecalciferol,Colecalciferol | Endogenous Metabolite |
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR). | |||
T28804 | Slingshot inhibitor D3 | JHN76359 | Others |
Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot. | |||
T38553 | Previtamin D3 | Previtamin D3 | |
Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3). | |||
T35501 | 5,6-trans-Vitamin D3 | 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A | Vitamin |
5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol) is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure. | |||
T12308 | Omeprazole-d3 | H 16868 D3 | Others |
Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI) | |||
T11853 | Linezolid-d3 | Linezolid D3,PNU-100766 D3 | Others |
Linezolid D3, a deuterium-labeled version of Linezolid, is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis. | |||
T6430 | Calcifediol | U 32070E,25-hydroxy Vitamin D3,RO 8-8892 | Endogenous Metabolite |
Calcifediol (U 32070E)(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA. | |||
T12135 | Mycophenolic acid-d3 | Mycophenolate-d3,Mycophenolate D3 | Others , Antibacterial |
Mycophenolic acid-d3 (Mycophenolate-d3) is a derivative of Mycophenolic acid. Mycophenolic acid is a compound that reduces GTP level and impacts transcription elongation of RNA polymerase II (RNAP II), promotes proximal ... | |||
T12487 | Piroxicam D3 | CP-16171 D3 | Others |
Piroxicam D3 is deuterium labeled Piroxicam. Piroxicam is a COX inhibitor(human monocyte COX-1 and COX-2 with IC50s of 47, 25 μM , respectively) . | |||
T12046 | Mirtazapine D3 | Org3770 D3,6-Azamianserin D3 | 5-HT Receptor |
Mirtazapine D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor . | |||
T11604 | Ibuprofen-d3 | Ibuprofen D3,(±)-Ibuprofen D3 | Others |
Ibuprofen D3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM). | |||
T16909 | Donafenib | Sorafenib (D3),Bay 43-9006 (D3),Sorafenib-d3 | Raf , VEGFR |
Donafenib (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively). | |||
T12691 | Rapamycin-d3 | AY-22989-d3,Sirolimus-d3 | Others |
Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells). | |||
T12018 | Methylnaltrexone-d3 bromide | Methylnaltrexone D3 Bromide | Others |
Methylnaltrexone D3 Bromide is the deuterium labeled Methylnaltrexone Bromide. | |||
T11692 | Ivabradine-d3 hydrochloride | Ivabradine D3 Hydrochloride | Others |
Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent. Ivabradine D3 Hydrochloride is the deuterium labeled Ivabradine hydrochloride. | |||
T24725 | ROCK-IN-D3 | ROCK inhibitor D3,ROCK-inhibitor-D3 | |
ROCK-IN-D3 is an effective and selective inhibitor of ROCK. |