cia — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T71534L	CIA-1 (Free base)	CIA-1(Free base）	Gamma-secretase
	CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenogr...		Gamma-secretase
T71534	CIA-1 hcl(452087-38-6 Free base)		Gamma-secretase
	CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII a...		Gamma-secretase
T2057	BVT 2733		Dehydrogenase
	BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.		Dehydrogenase
T4195	Betahistine	PT 9 base,Vasomotal,Serc base	Histamine Receptor
	Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti...		Histamine Receptor
T72006	DCAI Hydrochloride
	DCAI hydrochloride is an inhibitor of nucleotide exchange and nucleotide release, by binding to the pocket adjacent to the Ras-SOS interface.
T0246	Betahistine dihydrochloride	PT-9,Betahistine 2HCl	Histamine Receptor
	Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator.		Histamine Receptor
T2125	Trametinib	GSK1120212,JTP-74057	Apoptosis , MEK , Autophagy
	Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.		Apoptosis , MEK , Autophagy
T5857	Trametinib (DMSO solvate)	Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)	Apoptosis , MEK
	Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)		Apoptosis , MEK
T17870	cIAP1 ligand 1	E3 ligase Ligand 12	Others
	cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used to couple with androgen receptor ligands ...		Others
T68043	Ciamexon	Ciamexone,BM 41332,BM41332,BM-41332	Others
	Ciamexon (Ciamexone) is a novel immunomodulator that has shown promising results in experimental models of autoimmune disease with little demonstrated cytotoxicity.Ciamexon can be used to study endocrine ophthalmopathies...		Others
T21649L	GnRH Associated Peptide (GAP) (1-13), human Acetate	GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base)	Others
	GnRH Associated Peptide (GAP) (1-13), human Acetate was found to be a potent inhibitor of prolactin secretion and to stimulate the release of gonadotropins. Active immunization with peptides corresponding to GAP sequence...		Others
T5S2129	Sciadopitysin		TNF , NF-κB
	Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o...		TNF , NF-κB
T124855	Lucialdehyde A
	Lucialdehyde A is a useful organic compound for research related to life sciences and the catalog number is T124855.
T17889	cIAP1 Ligand-Linker Conjugates 14	E3 ligase Ligand-Linker Conjugates 36	Others
	cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1]...		Others
T17885	cIAP1 Ligand-Linker Conjugates 11	E3 ligase Ligand-Linker Conjugates 33	Others
	cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in ...		Others
TN2700	2,3-dihydrosciadopitysin		Others
	2,3-dihydrosciadopitysin is a natural product of Podocarpus, Podocarpaceae. The catalog number is TN2700 and the CAS number is 34421-19-7. 2,3-dihydrosciadopitysin can be used as a reference standard.		Others
T17869	cIAP1 ligand 2	E3 ligase Ligand 11	Others
	cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.		Others
T10496	Bencianol	ZY15051	Others
	Bencianol is a semisynthetic flavonoid with anti-spasmogenic activities.		Others
T30929	Cianopramine hydrochloride	Cianopramine HCl,Ro 112465 hydrochloride,Ro-11-2465 hydrochloride
	Cianopramine hydrochloride is a bio-active chemical.
T25248	Cianopramine	Ro 112465,Ro-112465,Ro112465
	Cianopramine is a tricyclic antidepressant and a potent neuronal serotonin (5-HT) uptake inhibitor in animals.