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Search Results for " cdd "

Targets

15

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T72058L CDD-1102 HCl CDD-1102 HCl(2757619-84-2 Free base) Epigenetic Reader Domain
CDD-1102 HCl is a novel BRDT-BD4 / BRD2-BD1302 selective inhibitor that shows non-hormonal contraceptive potential in ex vivo experiments.
T79344 CDD-1819 SARS-CoV
CDD-1819, a non-covalent and non-peptide compound, serves as a potent SARS-CoV-2 Mpro inhibitor, exhibiting a K i value of 5 nM. It also effectively inhibits the Mpro variants ΔP168, A173V, and ΔP168/A173V [1].
T79345 CDD-1733 SARS-CoV
CDD-1733 is a potent, non-covalent, and non-peptide inhibitor of the SARS-CoV-2 main protease (Mpro) with an inhibition constant (K i) of 12 nM. It effectively inhibits Mpro variants including ΔP168, A173V, and the combi...
T79346 CDD-1845 SARS-CoV
CDD-1845, a non-covalent, non-peptide inhibitor, exhibits potent inhibition of SARS-CoV-2 M^pro with a K_i value of 3 nM. Additionally, CDD-1845 is effective against M^pro variants ΔP168, A173V, and the combined ΔP168/A1...
T13600 CDD3505 4-nitro-1-trityl-1H-imidazole P450
CDD3505 (4-nitro-1-trityl-1H-imidazole) increases high-density lipoprotein cholesterol by targeting hepatic CYP3A.
T13601 CDD3506 1-TRITYL-1H-IMIDAZOL-4-AMINE P450
CDD3506 (1-TRITYL-1H-IMIDAZOL-4-AMINE) increases high-density lipoprotein cholesterol by targeting hepatic CYP3A.
T39126 Zunsemetinib CDD-450,ATI-450
Zunsemetinib (CDD-450) is a potent and specific inhibitor of the p38α-MK2 pathway, exerting its effects through oral administration. It has proven activity against immuno-inflammatory diseases, making it a valuable tool ...
TP2357 Ularitide CDD 95-126,ANP 95-126,Human urodilatin
Ularitide is a 32-amino acid peptide derived from (95-126 residues) of ANP PROHORMONE (1-126 residues). It isn't biologically inactivated by a peptidase from dog kidney cortex membranes.
T10731 CDD0102 CDD0102A AChR
CDD0102 is a potent agonist of M1 Muscarinic receptor.
T10733 CDDO-EA TP319,CDDO ethyl amide,RTA 405 Nrf2
CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.
TQ0120 CDDO-Im RTA-403,CDDO-Imidazolide,TP-235 Others , Ferroptosis , Nrf2 , PPAR
CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).
T13604 CDDO-dhTFEA Others , NF-κB , Nrf2
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expressi...
T80662 CDD0102 HCl CDD0102A HCl AChR
CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.
T13603 CDDO-3P-Im Necroptosis
CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion.
T13602 CDDO-2P-Im CDDO-2-P-Im Others
CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00925 SOST Protein, Human, Recombinant (His) Human HEK293 Cells
SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPY-05113 SOST Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
SOST Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPK-01293 SOST Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ...
TMPH-01178 CDA Protein, Human, Recombinant (His & Myc) Human E. coli
CDA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPK-00102 SOST Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ...
TMPK-00103 SOST Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ...
TMPY-03046 APCDD1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res...
TMPK-00989 APCDD1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
APCDD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q3U128.
TMPK-00311 APCDD1 Protein, Human, Recombinant (His) Human HEK293 Cells
APCDD1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q8J025.
TargetMol