Search Result

Search Results for " cd86 "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Targets
T61810	Anti-inflammatory agent 16
	Anti-inflammatory agent 16 (compound 14) is a highly effective peptidomimetic with potent anti-inflammatory properties. It effectively reduces the expression levels of TNFα, NO, CD40, and CD86 [1].
T62099	LSD1-IN-13
	LSD1-IN-13 (compound 7e) is an orally active LSD1 inhibitor (IC50: 24.43 nM) that also activates CD86 expression (EC50: 470 nM).LSD1-IN-13 induces differentiation of AML (acute myeloid leukaemia) cell lines.
T73318	BTK-IN-18
	BTK-IN-18 is a potent, reversible inhibitor of Bruton's tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 µM. Additionally, it effectively suppresses CD69 and CD86 expression in vivo.
T74915	ODN D-SL03
	ODN D-SL03, a class C CpG oligonucleotide, effectively stimulates peripheral blood mononuclear cells (PBMCs) to produce high levels of IFN-α. It activates human B cells, NK cells, and mononuclear cells, elevating the exp...
T74907	ODN 21595
	ODN 21595, a guanine-modified inhibitor targeting TLR7 and TLR9, effectively inhibits the release of IFN-α and IL-6 without exhibiting cytotoxicity. It also reduces the expression of CD86 and HLA-DR, showcasing potential...
T83866	LCC-12 formate
	LCC-12, a derivative of the biguanide metformin, acts as a copper (II) chelator. It efficiently forms a monomeric bond with copper (II) and at 20 µM, it mitigates hydrogen peroxide-induced oxidation from NADH to NAD+. At...
T62679	LSD1-IN-13 hydrochloride
	LSD1-IN-13 hydrochloride (compound 7e) is an orally active inhibitor of LSD1 (IC50: 24.43 nM). hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines.
T36984	Cyclic di-IMP (sodium salt)
	Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP . C-di-IMP has adjuvant properties when co-administered with ...
T15365	G-744	BTK
	G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM). G-744 is well-tolerated, metabolically stable. It also has an efficacious to treat arthritis.	BTK

Compounds

Anti-inflammatory agent 16

LSD1-IN-13 hydrochloride

T62679

Synonym:

Target:

Cyclic di-IMP (sodium salt)

Cat No.	Product Name	Synonyms	Targets
TN5912	Macluraxanthone	3-Hydroxyblancoxanthone	Antioxidant , TNF
	Macluraxanthone (3-Hydroxyblancoxanthone) has many biological activities including anticholinesterase, antioxidant, anticancer, antimalarial, anti-inflammatory and immunomodulatory effects. macluraxanthone promotes the p...		Antioxidant , TNF

Natural Products

Macluraxanthone

TN5912

Synonym: 3-Hydroxyblancoxanthone

Target: Antioxidant, TNF

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01180	CD86 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-02016	CD86 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	CD86 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A9K3Y6P6.
TMPY-03646	CD86 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	CD86 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is Q9BDM4.
TMPY-03562	CD86 Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293 Cells
	CD86 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is Q9BDM4.
TMPY-05390	CD86 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.9 kDa and the accession number is A0A0X9R4E0.
TMPY-05246	CD86 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P42081-3.
TMPY-06880	CD86 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.42 kDa and the accession number is NP_008820.4.
TMPY-01206	CD86 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD86 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P42082-1.
TMPY-05386	CD86 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD86 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is P42082-1.
TMPY-05133	CD86 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	CD86 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is P42082-1.
TMPJ-00959	B7-2 Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
	B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.
TMPK-00882	B7-2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPJ-00641	B7-2 Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
	B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the accession number is H9ZFI8.
TMPJ-00632	B7-2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4.
TMPK-00653	B7-2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00880	B7-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00881	B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPJ-00556	B7-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	B7-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 57-66 KDa and the accession number is AAH40261.1.
TMPJ-00555	B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is AAH40261.1.
TMPK-00110	CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)	Human,Cynomolgus,Rhesus	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting...
TMPK-01176	CD28 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting...
TMPK-01177	CD28 Protein, Canine, Recombinant (mFc)	Canine	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting...
TMPK-00111	CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated	Human,Cynomolgus,Rhesus	HEK293 Cells
	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting...
TMPJ-00099	CD28 Protein, Mouse, Recombinant (hFc & His)	Mouse	HEK293 Cells
	T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the recep...
TMPK-00112	CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T...
TMPY-02555	VSTM1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds ...
TMPY-02563	VSTM1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds ...
TMPJ-00219	BTN3A2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Butyrophilin subfamily 3 member A2, also known as BT3.2, BTF3, BTF4 and BTN3A2, is a single-pass type I membrane protein. It is a member of the butyrophilin (BTN) family and the immunoglobulin (IG) superfamily. Mature hu...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their recep...
TMPJ-00420	CTLA-4 Protein, Mouse, Recombinant (Flag)	Mouse	HEK293 Cells
	Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory pro...
TMPH-02841	Prohibitin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regul...
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and...