Search Result

Search Results for " bad "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T40412L	BAD (103-127) (human) acetate	BAD (103-127) (human) acetate (331762-68-6 Free base)	Others
	BAD (103-127) (human) acetate is a 25-mer Bad polypeptide from the BAD BH3 domain that antagonizes the effects of Bcl-xl.		Others
T40412	BAD (103-127) (human)
	BAD (103-127) (human) is a 25-mer peptide obtained from the BH3 domain of BAD. It effectively counteracts the activity of Bcl-xL. Notably, BAD (103-127) (human) exhibits an approximately 800-fold greater binding affinity...
T80223	Bad BH3 (mouse)
	Bad BH3 (mouse) is a bioactive peptide derived from the BH3 domain (a death domain) of Bad, encompassing amino acid residues 140 to 165, and functions by binding to bcl-2.
T76082	BAD (103-127) (human), FAM-labeled
	BAD (103-127) (human), FAM-labeled, is a FAM-labeled 25-mer peptide derived from the BH3 domain of human BAD. This peptide can antagonize the function of Bcl-xL [1].
T1834	CX-6258	CX 6258	Pim
	CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.		Pim
T6148	CX-6258 hydrochloride	CX-6258 HCl,Pim-Kinase Inhibitor X	Pim
	CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).		Pim
T8978	DD1	3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome
	DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
T22596	BADGE		PPAR
	PPARγ antagonist		PPAR
T0770	Carbadox	Getroxel,Mecadox	Antibacterial , Antibiotic
	Carbadox (Mecadox) is an antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibited in the UK following reports...		Antibacterial , Antibiotic
T35760	Carnaubadiol
	Carnaubadiol is a triterpene that has been found in E. corollata and has antiprotozoal activities.1,2 It is active against L. infantum promastigotes and amastigotes, as well as T. cruzi trypomastigotes (IC50s = 46.2, 7.8...
T33404	MitoBADY	Mito-BADY,Mito BADY
	Mitobady is a sensitive and specific Raman probe, which can be used for living cell imaging of mitochondria.
T40635	Desoxycarbadox
	Desoxycarbadox, derived from Carbadox, is a quinoxaline-di-N-oxide antibiotic compound.
T78067	Stobadine	(-)-Stobadine	Reactive Oxygen Species
	Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes. It shows promise in the development of cardio- and neuroprotective agents owing to its mechan...		Reactive Oxygen Species
T14498	Barbadin		Arrestin
	Barbadin is a novel and specific inhibitor of β-arrestin/β2-adaptin interaction with an IC50 value of 19.1 μM for β-arestin1 and 15.6 μM for β-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC ne...		Arrestin
T12249	NPB	Alpha-NPB	Others
	NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)		Others
TP2127	R18
	Antagonist of 14.3.3 proteins (KD ≈80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzy...
TP2128	R8-T198wt
	Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27Kip1. Inhibits Pim-1 phosphorylation of p27Kip1 and Bad; induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. Also inhibits Pim...
T71230	VMY-1-103
	VMY-1-103 is a potent CDK inhibitor, is also a novel dansylated analog of purvalanol B, was shown to inhibit cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B...

Compounds

BAD (103-127) (human) acetate

T40412L

Synonym: BAD (103-127) (human) acetate (331762-68-6 Free base)

Target: Others

BAD (103-127) (human)

BAD (103-127) (human), FAM-labeled

CX-6258 hydrochloride

T6148

Synonym: CX-6258 HCl,Pim-Kinase Inhibitor X

Target: Pim

DD1

T8978

Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111

Synonym: Getroxel,Mecadox

Target: Antibacterial, Antibiotic

Synonym: Mito-BADY,Mito BADY

Synonym: (-)-Stobadine

Target: Reactive Oxygen Species

Cat No.	Product Name	Synonyms	Targets
T15258	Euphorbadienol	alpha-Euphorbol	Others
	Euphorbadienol is a triterpenic compound isolated from the latex of Euphorbia resinifera. It has antileishmanial and antitrypanosomal activity.		Others
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T4827	Trimethylammonium chloride	Trimethylamine hydrochloride	Others , Endogenous Metabolite
	Trimethylammonium chloride (Trimethylamine hydrochloride) is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagin...		Others , Endogenous Metabolite
TN6419	Chamaejasmine
	Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and ind...

Natural Products

Euphorbadienol

T15258

Synonym: alpha-Euphorbol

Target: Others

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Trimethylammonium chloride

T4827

Synonym: Trimethylamine hydrochloride

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-01234	LAMP5 Protein, Human, Recombinant (His)	Human	HEK293
	Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPK-00659	LAMP5 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPK-01161	LAMP5 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPK-01233	LAMP5 Protein, Human, Recombinant (hFc)	Human	HEK293
	Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPH-00852	HIBADH Protein, Human, Recombinant (His & Myc)	Human	E. coli
	HIBADH Protein, Human, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 39.0 kDa. Accession number: P31937
TMPK-00811	L1CAM Protein, Mouse, Recombinant (His)	Mouse	HEK293
	L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many huma...
TMPJ-00014	Resistin Protein, Human, Recombinant (His)	Human	E. coli
	Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPJ-00684	SNCA Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's ...
TMPH-01692	MAPK3 Protein, Human, Recombinant (His)	Human	E. coli
	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...