store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Barbadin is a novel and specific inhibitor of β-arrestin/β2-adaptin interaction with an IC50 value of 19.1 μM for β-arestin1 and 15.6 μM for β-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic β2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | In stock | $ 199.00 |
Description | Barbadin is a novel and specific inhibitor of β-arrestin/β2-adaptin interaction with an IC50 value of 19.1 μM for β-arestin1 and 15.6 μM for β-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic β2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity. |
Targets&IC50 | β-arrestin2:15.6 μM, β-arrestin1:19.1 μM |
Molecular Weight | 333.41 |
Formula | C19H15N3OS |
CAS No. | 356568-70-2 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (89.98 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Barbadin 356568-70-2 GPCR/G Protein Arrestin inhibitor inhibit