bart — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T74427	Paridiprubart
	Paridiprubart (NI-0101), a humanized monoclonal antibody targeting TLR4, offers promising research avenues for rheumatoid arthritis [1].
T82461	Epacmarstobart	GS-0189,FSI-189
	Epacmarstobart (FSI-189; GS-0189) is a chimeric humanized IgG1κ antibody designed to target the mouse Signal Regulatory Protein Alpha (SIRPA).
T82474	Empasiprubart	ARGX-117
	Empasiprubart (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. It inhibits the formation of C3 proconvertase, obstructing classical and lectin pathway activation by binding to the Sushi-2...
T82268	Gotistobart	BNT 316,ONC-392
	Gotistobart (ONC-392) is a humanized anti-CTLA-4 antibody that enhances immunotherapy by selectively depleting regulatory T cells (Treg) within the tumor microenvironment [1].
T82946	Atisnolerbart
	Atisnolerbart, a human IgG4 antibody, specifically targets BETVIA, which is identified as the major birch pollen allergen, Bet v 1-A.
T82371	Freneslerbart
	Freneslerbart, an IgG4κ antibody, specifically targets Felcat allergen 1, an allergenic protein [1].
T81610	Oloctinebart
	Oloctinebart, a humanized immunoglobulin G4-kappa (IgG4-κ) monoclonal antibody targeting LGALS3, is utilized to decrease the formation of amyloid beta oligomers [1].
T80918	Tuparstobart	Incagn-02385
	Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic ...
T80564	Vamikibart
	Vamikibart is a chimeric, humanized IgG2κ antibody that targets IL6 [1].
T81260	Rolistobart
	Rolistobart is a humanized IgG4-κ monoclonal antibody targeting LILRB4/CD85k. It functions as an immunostimulant and antineoplastic agent [1].
T81805	Mevonlerbart
	Mevlonerbart, an IgG4κ antibody, specifically targets human Felcat allergen 1, an allergen protein.
T78659	Crexavibart	BMS-986413,C-144-LS	SARS-CoV
	Crexavibart (BMS-986413; C-144-LS), an IgG1 λ2 antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].		SARS-CoV
T81022	Tegoprubart
	Tegoprubart is a monoclonal antibody targeting CD40 ligand (CD40L), which plays a critical role in costimulation. By inhibiting CD40L, it diminishes both cellular and antibody-mediated immune responses, fostering a more ...
T80572	Exlinkibart	LVGN-6051
	Exlinkibart (LVGN-6051) is a humanized IgG1κ antibody that selectively targets TNFRSF9, utilizing complementarity-determining region (CDR) grafting technology for its humanization.
T81124	Sovipostobart
	Sovipostobart, an immunoglobulin G1-kappa monoclonal antibody targeting CTLA-4 in Homo sapiens, features a cleavable prodomain. This compound serves as both an immunostimulant and antineoplastic [1].
T80571	Eurestobart		Phosphatase
	Eurestobart is a humanized IgG1κ (IgG1 kappa) monoclonal antibody that specifically targets the enzyme ectonucleoside triphosphate diphosphohydrolase (ENTPDase).		Phosphatase
T82077	Iluzanebart
	Iluzanebart is a human IgG1κ monoclonal antibody that selectively targets TREM2—a triggering receptor expressed on myeloid cells [1].
T80902	Umesolerbart
	Umesolerbart (REGN5714) is a monoclonal antibody (mAb) specific to Bet v1 that also binds to homologous allergens in Alder, Hazel, and Hornbeam [1].
T81928	Lipustobart		PD-1/PD-L1
	Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplastic activity [1].		PD-1/PD-L1
T81925	Lixudebart
	Lixudebart is a humanized IgG1-kappa monoclonal antibody that targets CLDN1 [1].
T80903	Ulviprubart	ABC-008
	Ulviprubart, an anti-KLRG1 monoclonal antibody (mAb), is utilized in various disease research [1].
T80575	Simaravibart	MAD-0004J08	SARS-CoV
	Simaravibart (MAD-0004J08), an IgG1κ monoclonal antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].		SARS-CoV
T80560	Tulisokibart	PRA-023,PRA023
	Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody that targets TNFSF15/TL1A, with potential applications in researching various inflammatory and fibrotic diseases, including Crohn's Disease (CD) [1] [2].
T80959	Trabikibart	CSL311
	Trabikibart (CSL311), a βc-specific, fully human monoclonal antibody, specifically binds to the cytokine-binding epitope of the human βc receptor with picomolar affinity. It potently inhibits the collective impact of IL-...
T80577	Varokibart
	Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1].
T80868	Verzistobart
	Verzistobart, an IgG1κ antibody, specifically targets the hepatitis A virus cellular receptor, HAVCR2.
T74424	Masavibart
	Masavibart (ZRC3308-A7), an IgG1 type anti-SARS-CoV-2 monoclonal antibody, demonstrates strong binding affinity for a distinct non-competing epitope located on the receptor-binding domain (RBD) of the SARS-CoV-2 spike pr...
T74425	Nepuvibart
	Nepuvibart (ZRC3308-B10), an IgG1 type anti-SARS-CoV-2 monoclonal antibody, exhibits strong binding affinity to a distinct non-competing epitope on the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. When ...
T82615	Dalnicastobart	LVGN-7409
	Dalnicastobart (LVGN-7409) is a human IgG1κ monoclonal antibody that specifically targets CD40, also known as TNFRSF5 [1].
T82465	Enlonstobart
	Enlonstobart is a humanized IgG4-κ monoclonal antibody targeting PDCD1, functioning as both an immunostimulant and antineoplastic agent [1].
T82409	Fepixnebart
	Fepixnebart is a humanized IgG4κ antibody that targets TGF-alpha (TGFA).
T80576	Picankibart
	Picankibart is a mouse-origin monoclonal antibody (IgG1κ) that targets interleukin 23A (IL23A) [1].
T80970	Tobevibart		HBV
	Tobevibart, an IgG1-lambda humanized monoclonal antibody targeting the hepatitis B virus (HBV) surface envelope protein, exhibits antiviral activity [1].		HBV
T80566	Temtokibart
	Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.
T81314	Rademikibart	CBP-201
	Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without cross-reactivity to IL-4Rα from other species. It effectively...
T81410	Prafnosbart	DS-6016A
	Prafnosbart (DS-6016A) is a humanized IgG1-kappa monoclonal antibody targeting ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1), utilized in research on bone metabolism disorders [1].
T81538	Patecibart		Endothelin Receptor
	Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).		Endothelin Receptor
T81297	Renvistobart
	Renvistobart is a monoclonal antibody belonging to the immunoglobulin G1-κ class, targeting the human T cell immunoreceptor with Ig and ITIM domains (TIGIT, also known as VSIG9 or VSTM3) [1].
T80578	Evunzekibart	ATOR-1017
	Evunzekibart (ATOR-1017) is an Fc-γ receptor-dependent 4-1BB agonist and an IgG4 isotype antibody. It can function as a monotherapy or synergize with anti-PD1 therapies to promote anti-tumor effects.
T80569	Benmelstobart		PD-1/PD-L1
	Benmelstobart, an IgG1κ antibody, targets PD-L1/CD274 and is of murine origin [1].		PD-1/PD-L1
T80570	Dazukibart		IFNAR
	Dazukibart is a humanized IgG1κ monoclonal antibody of murine origin, specifically targeting interferon beta 1 (IFNB1) [1].		IFNAR
T25138	Barthrin
	Barthrin is used as an Experimental Pesticide.
T74426	Ogalvibart
	Ogalvibart (C-135-LS), a humanized anti-SARS-CoV-2 IgG1 type monoclonal antibody, specifically targets and binds to the spike (S) glycoprotein receptor-binding domain (RBD) of the SARS-CoV-2 virus. When combined with C14...
T82820	Bremzalerbart
	Bremzalerbart is a human IgG4 antibody that targets BETVIA, which is the primary allergen Bet v 1-A [1] in birch pollen.
T82994	Anzurstobart	BMS-986351,CC-95251
	Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture ass...
T82589	Delpacibart
	Delpacibart is a humanized mouse IgG1κ antibody that targets TFRC, a critical membrane protein regulating intracellular iron transport [1].
T82899	Bempikibart	ADX-914
	Bempikibart (ADX-914), a human anti-IL-7Rα antibody, has potential applications in anti-inflammatory research [1].
T82440	Erzotabart		CD38
	Erzotabart, an IgG1-kappa monoclonal antibody targeting CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1) in Homo sapiens, exhibits antineoplastic activity [1].		CD38
T81098	Stapokibart	CM310
	Stapokibart (CM310), a humanized monoclonal antibody, selectively binds to IL-4Rα, inhibiting the cytokines IL-4 and IL-13 from interacting with their shared co-receptor subunit, IL-4Rα. This compound demonstrates cross-...
T80618	Narlumosbart		RANKL/RANK
	Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].		RANKL/RANK

Compounds

Paridiprubart

T74427

Synonym: GS-0189,FSI-189

Synonym: BNT 316,ONC-392

Synonym: Incagn-02385

Synonym: BMS-986413,C-144-LS

Synonym: PRA-023,PRA023

Target: Endothelin Receptor

Synonym: BMS-986351,CC-95251

Cat No.	Product Name	Species	Expression System
TMPY-03500	ARL2BP Protein, Human, Recombinant (His)	Human	E. coli
	ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activ...

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Compounds

Recombinant Proteins

Compounds

Recombinant Proteins